Stability of SARS-CoV-2 phylogenies

Y Turakhia, N De Maio, B Thornlow, L Gozashti… - PLoS …, 2020 - journals.plos.org
The SARS-CoV-2 pandemic has led to unprecedented, nearly real-time genetic tracing due
to the rapid community sequencing response. Researchers immediately leveraged these …

Emergence of genomic diversity and recurrent mutations in SARS-CoV-2

L Van Dorp, M Acman, D Richard, LP Shaw… - Infection, Genetics and …, 2020 - Elsevier
SARS-CoV-2 is a SARS-like coronavirus of likely zoonotic origin first identified in December
2019 in Wuhan, the capital of China's Hubei province. The virus has since spread globally …

Assessing uncertainty in the rooting of the SARS-CoV-2 phylogeny

L Pipes, H Wang, JP Huelsenbeck… - Molecular biology and …, 2021 - academic.oup.com
The rooting of the SARS-CoV-2 phylogeny is important for understanding the origin and
early spread of the virus. Previously published phylogenies have used different rootings that …

[HTML][HTML] Issues with SARS-CoV-2 sequencing data

N De Maio, C Walker, R Borges, L Weilguny… - 2020 - virological.org
We investigate oddities in the SARS-CoV-2 genome sequences from GISAID. Many putative
sequencing issues seem specific to genomic ends and to certain samples, and are easily …

Temporal dynamics of SARS-CoV-2 mutation accumulation within and across infected hosts

AL Valesano, KE Rumfelt, DE Dimcheff, CN Blair… - PLoS …, 2021 - journals.plos.org
Analysis of SARS-CoV-2 genetic diversity within infected hosts can provide insight into the
generation and spread of new viral variants and may enable high resolution inference of …

[PDF][PDF] Mutation rates and selection on synonymous mutations in SARS-CoV-2

N De Maio, CR Walker, Y Turakhia… - Genome biology and …, 2021 - academic.oup.com
The COVID-19 pandemic has seen an unprecedented response from the sequencing
community. Leveraging the sequence data from more than 140,000 SARS-CoV-2 genomes …

HAVoC, a bioinformatic pipeline for reference-based consensus assembly and lineage assignment for SARS-CoV-2 sequences

PT Truong Nguyen, I Plyusnin, T Sironen… - BMC …, 2021 - Springer
Background SARS-CoV-2 related research has increased in importance worldwide since
December 2019. Several new variants of SARS-CoV-2 have emerged globally, of which the …

[HTML][HTML] Evolutionary analysis and lineage designation of SARS-CoV-2 genomes

X Tang, R Ying, X Yao, G Li, C Wu, Y Tang, Z Li… - Science bulletin, 2021 - Elsevier
The pandemic due to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
the etiological agent of coronavirus disease 2019 (COVID-19), has caused immense global …

Evolutionary tracking of SARS-CoV-2 genetic variants highlights an intricate balance of stabilizing and destabilizing mutations

JJ Jacob, K Vasudevan, AK Pragasam, K Gunasekaran… - MBio, 2021 - Am Soc Microbiol
The currently ongoing COVID-19 pandemic caused by SARS-CoV-2 has accounted for
millions of infections and deaths across the globe. Genome sequences of SARS-CoV-2 are …

Phylogenetic analysis of SARS-CoV-2 data is difficult

B Morel, P Barbera, L Czech… - Molecular biology …, 2021 - academic.oup.com
Numerous studies covering some aspects of SARS-CoV-2 data analyses are being
published on a daily basis, including a regularly updated phylogeny on nextstrain. org. Here …