The antimicrobial activity of human β-defensin 3 (hBD-3) against multidrug-resistant clinical
isolates of Staphylococcus aureus, Enterococcus faecium, Pseudomonas aeruginosa …

Human neutrophil defensins, and their analogues incorporating anionic, hydrophobic or
cationic residues at the N-and C-termini, were synthesized by solid-phase procedures. The …

The human intestinal tract is constantly exposed to an enormous indigenous bacterial flora.
It has recently been recognised that antimicrobial peptides of the defensin family likely play …

Mucosal surfaces of several organ systems are important interfaces for host defense against
microbes. Recent evidence suggests that antimicrobial peptides contribute to the defense of …

Human beta defensin 2 (HBD-2), the most recently discovered human defensin, has been
considered to work as a host defense substance against microbial infection. Using …

The defensins knowledgebase is a manually curated database and information source
focused on the defensin family of antimicrobial peptides. The current version of the database …

Defensins were first identified in 1985 and are now recognized as part of a large family of
antimicrobial peptides, divided into three categories: α-, β-, and θ-defensins. These defensin …

Background: Defensins, a major family of antimicrobial peptides, are small cationic, cysteine-
rich peptides with a wide range of antimicrobial activity. In human, β-defensin-1 was isolated …

Human β-defensin-2 (HBD-2) is a member of the defensin family of antimicrobial peptides.
HBD-2 was first isolated from inflamed skin where it is posited to participate in the killing of …

Defensins are cationic antimicrobial mini-proteins that play important roles in the innate
immune defense against microbial infection. Six invariant Cys residues in each defensin …