Correlation between blood and CSF compartment cytokines and chemokines in subjects with cryptococcal meningitis

EC Okafor, KH Hullsiek, DA Williams… - Mediators of …, 2020 - Wiley Online Library
Background. Though peripheral blood is a crucial sample to study immunology, it is unclear
whether the immune environment in the peripheral vasculature correlates with that at the …

Immune mediators in cerebrospinal fluid during cryptococcosis are influenced by meningeal involvement and human immunodeficiency virus serostatus

O Lortholary, F Dromer… - The Journal of …, 2001 - academic.oup.com
Pro-and anti-inflammatory mediators (tumor necrosis factor [TNF]—α, interleukin [IL]—6, IL-8,
IL-10, and soluble TNF receptor II [sTNFR] II) were measured in cerebrospinal fluid (CSF) …

Cerebrospinal fluid cytokine and chemokine patterns correlate with prognosis of HIV-uninfected cryptococcal meningitis: A prospective observational study

YK Jiang, RY Wang, LH Zhou, JH Cheng… - Frontiers in …, 2022 - frontiersin.org
The cerebrospinal fluid (CSF) immune responses in HIV-uninfected cryptococcal meningitis
(CM) have not been well studied. In this study, we aimed to explore the phenotype of CSF …

Cytokine profiles in cerebrospinal fluid of human immunodeficiency virus—infected patients with cryptococcal meningitis: no leukocytosis despite high interleukin-8 …

W Chaka, R Heyderman, I Gangaidzo… - Journal of Infectious …, 1997 - academic.oup.com
Cytokine levels were studied in the cerebrospinal fluid (CSF) of 16 adults with cryptococcal
meningitis (CM). Low levels of tumor necrosis factor (TNF)-α and interferon-γ, high levels of …

Cerebrospinal fluid cytokine profiles predict risk of early mortality and immune reconstitution inflammatory syndrome in HIV-associated cryptococcal meningitis

JN Jarvis, G Meintjes, T Bicanic, V Buffa… - PLoS …, 2015 - journals.plos.org
Understanding the host immune response during cryptococcal meningitis (CM) is of critical
importance for the development of immunomodulatory therapies. We profiled the …

CSF Cytokines and Chemokines Involved in Cytotoxic Cell Function and Risk of Acute 14-Day Mortality in Persons with Advanced HIV and Cryptococcal Meningitis

EC Okafor, L Mukaremera, KH Hullsiek… - The Journal of …, 2024 - academic.oup.com
Background Despite availability of HIV treatment globally, cryptococcal meningitis continues
to cause considerable morbidity and mortality. The role of the immune response in acute …

Cytokine patterns in a prospective cohort of HIV-infected patients with cryptococcal meningitis following initiation of antifungal and antiretroviral therapy

DJ Mora, K Ferreira-Paim, LE Andrade-Silva… - PLoS …, 2017 - journals.plos.org
Cryptococcal meningitis (CM) is a life-threatening infection in HIV-infected patients,
especially in resource-limited settings. Cytokine patterns in the cerebrospinal fluid (CSF) …

Variables that influence HIV-1 cerebrospinal fluid viral load in cryptococcal meningitis: a linear regression analysis

DM Cecchini, AM Cañizal, H Rojas… - Journal of the …, 2009 - Springer
Background The central nervous system is considered a sanctuary site for HIV-1 replication.
Variables associated with HIV cerebrospinal fluid (CSF) viral load in the context of …

Increased activity of the complement system in cerebrospinal fluid of the patients with Non-HIV Cryptococcal meningitis

L Shen, J Zheng, Y Wang, M Zhu, H Zhu… - BMC infectious …, 2017 - Springer
Backgrounds Cryptococcal meningitis (CM) has been known to lead to significant morbidity
and mortality. The relative contribution of the complement system in protection and …

Cytokine profiles at admission can be related to outcome in AIDS patients with cryptococcal meningitis

DJ Mora, LR Fortunato, LE Andrade-Silva… - PloS one, 2015 - journals.plos.org
Cryptococcal meningitis (CM) remains as common life-threatening AIDS-defining illness
mainly in resource-limited settings. Previous reports suggested that baseline cytokine …