Bromelain's activity and potential as an anti-cancer agent: current evidence and perspectives
K Chobotova, AB Vernallis, FAA Majid - Cancer letters, 2010 - Elsevier
The medicinal qualities of pineapple are recognized in many traditions in South America,
China and Southeast Asia. These qualities are attributed to bromelain, a 95%-mixture of …
China and Southeast Asia. These qualities are attributed to bromelain, a 95%-mixture of …
Bromelain: biochemistry, pharmacology and medical use
HR Maurer - Cellular and Molecular Life Sciences CMLS, 2001 - Springer
Bromelain is a crude extract from the pineapple that contains, among other components,
various closely related proteinases, demonstrating, in vitro and in vivo, antiedematous …
various closely related proteinases, demonstrating, in vitro and in vivo, antiedematous …
Bromelain and N-acetylcysteine inhibit proliferation and survival of gastrointestinal cancer cells in vitro: significance of combination therapy
A Amini, S Masoumi-Moghaddam, A Ehteda… - Journal of Experimental …, 2014 - Springer
Background Bromelain and N-acetylcysteine are two natural, sulfhydryl-containing
compounds with good safety profiles which have been investigated for their benefits and …
compounds with good safety profiles which have been investigated for their benefits and …
Anticancer properties of bromelain: State-of-the-art and recent trends
Bromelain is a key enzyme found in pineapple (Ananas comosus (L.) Merr.); a proteolytic
substance with multiple beneficial effects for human health such as anti-inflammatory …
substance with multiple beneficial effects for human health such as anti-inflammatory …
On the pharmacology of bromelain: an update with special regard to animal studies on dose-dependent effects
H Lotz-Winter - Planta medica, 1990 - thieme-connect.com
Bromelain, a standardized complex of proteases from the pineapple plant, is absorbed
unchanged from the intestine of animals at a rate of 40%; in animal experiments it was found …
unchanged from the intestine of animals at a rate of 40%; in animal experiments it was found …
Anticancer property of bromelain with therapeutic potential in malignant peritoneal mesothelioma
K Pillai, J Akhter, TC Chua, DL Morris - Cancer investigation, 2013 - Taylor & Francis
Bromelain is a mixture of proteolytic enzymes that is capable of hydrolyzing glycosidic
linkages in glycoprotein. Glycoprotein's are ubiquitously distributed throughout the body and …
linkages in glycoprotein. Glycoprotein's are ubiquitously distributed throughout the body and …
[HTML][HTML] Potentiation of chemotherapeutics by bromelain and N-acetylcysteine: sequential and combination therapy of gastrointestinal cancer cells
A Amini, S Masoumi-Moghaddam… - American journal of …, 2016 - ncbi.nlm.nih.gov
Intraperitoneal chemotherapy together with cytoreductive surgery is the standard of care for
a number of peritoneal surface malignancies. However, this approach fails to maintain the …
a number of peritoneal surface malignancies. However, this approach fails to maintain the …
[HTML][HTML] Bromelain: a potent phytomedicine
The commercially available protein-digesting enzyme bromelain is derived from the
pineapple fruit or stem. Bromelain from fruit and stems are produced in different ways and …
pineapple fruit or stem. Bromelain from fruit and stems are produced in different ways and …
In vivo antitumoral activity of stem pineapple (Ananas comosus) bromelain
R Báez, MTP Lopes, CE Salas, M Hernández - Planta medica, 2007 - thieme-connect.com
Abstract Stem bromelain (EC 3.4. 22.32) is a major cysteine proteinase, isolated from
pineapple (Ananas comosus) stem. Its main medicinal use is recognized as digestive, in …
pineapple (Ananas comosus) stem. Its main medicinal use is recognized as digestive, in …