The intestinal virome and immunity

JA Neil, K Cadwell - The Journal of Immunology, 2018 - journals.aai.org
The composition of the human microbiome is considered a major source of interindividual
variation in immunity and, by extension, susceptibility to diseases. Intestinal bacteria have …

Gut inflammation and immunity: what is the role of the human gut virome?

A Focà, MC Liberto, A Quirino… - Mediators of …, 2015 - Wiley Online Library
The human virome comprises viruses that infect host cells, virus‐derived elements in our
chromosomes, and viruses that infect other organisms, including bacteriophages and plant …

Gut virome: role and distribution in health and gastrointestinal diseases

L Spencer, B Olawuni, P Singh - Frontiers in cellular and infection …, 2022 - frontiersin.org
The study of the intestinal microbiome is an evolving field of research that includes
comprehensive analysis of the vast array of microbes–bacterial, archaeal, fungal, and viral …

[HTML][HTML] The dark side of the gut: Virome–host interactions in intestinal homeostasis and disease

Y Li, SA Handley, MT Baldridge - Journal of Experimental Medicine, 2021 - rupress.org
The diverse enteric viral communities that infect microbes and the animal host collectively
constitute the gut virome. Although recent advances in sequencing and analysis of …

Crosstalk between the intestinal virome and other components of the microbiota, and its effect on intestinal mucosal response and diseases

NA Clinton, SA Hameed, EK Agyei… - Journal of …, 2022 - Wiley Online Library
In recent years, there has been ample evidence illustrating the effect of microbiota on gut
immunity, homeostasis, and disease. Most of these studies have engaged more efforts in …

Beyond the gut bacterial microbiota: The gut virome

P Columpsi, P Sacchi, V Zuccaro… - Journal of medical …, 2016 - Wiley Online Library
The gastrointestinal tract is colonized with a highly different population of bacterial, viral, ad
fungal species; viruses are reported to be dominant. The composition of gut virome is closely …

Transkingdom control of viral infection and immunity in the mammalian intestine

JK Pfeiffer, HW Virgin - Science, 2016 - science.org
BACKGROUND Viruses that infect the mammalian gastrointestinal tract have intimate
relationships with the host, as well as members of the complex community of microbes that …

The human intestinal virome in health and disease

SR Carding, N Davis, L Hoyles - Alimentary pharmacology & …, 2017 - Wiley Online Library
Background The human virome consists of animal‐cell viruses causing transient infections,
bacteriophage (phage) predators of bacteria and archaea, endogenous retroviruses and …

[HTML][HTML] The virome in host health and disease

K Cadwell - Immunity, 2015 - cell.com
The mammalian virome includes diverse commensal and pathogenic viruses that evoke a
broad range of immune responses from the host. Sustained viral immunomodulation is …

Enteric viruses evoke broad host immune responses resembling those elicited by the bacterial microbiome

S Dallari, T Heaney, A Rosas-Villegas, JA Neil… - Cell host & …, 2021 - cell.com
The contributions of the viral component of the microbiome—the virome—to the
development of innate and adaptive immunity are largely unknown. Here, we systematically …