[PDF][PDF] Experimental and computational study of biological activities of alkaloids isolated from Peganum harmala seeds

F Lamchouri, H Toufik, SM Bouzzine… - Journal of Materials …, 2010 - jmaterenvironsci.com
Anticancer compounds from natural products were screened using tumor cell lines. In the
present study, we investigated the antiproliferative activity of four compounds isolated from …

[PDF][PDF] In-silico activity prediction and docking studies of some 2, 9-disubstituted 8-phenylthio/phenylsulfinyl-9h-purine derivatives as Anti-proliferative agents

MT Ibrahim, A Uzairu, GA Shallangwa, S Uba - Heliyon, 2020 - cell.com
In-silico activity prediction was performed to predict new inhibitory activities of 2, 9-
disubstituted 8-phenylthio/phenylsulfinyl-9h-purine derivatives as anti-proliferative agents …

Marine steroids as potential anticancer drug candidates: In silico investigation in search of inhibitors of Bcl-2 and CDK-4/Cyclin D1

S Saikia, B Kolita, PP Dutta, DJ Dutta, S Nath… - Steroids, 2015 - Elsevier
Star fishes (Asteroidea) are rich in polar steroids with diverse structural characteristics. The
structural modifications of star fish steroids occur at 3β, 4β, 5α, 6α (or β), 7α (or β), 8, 15α (or …

[HTML][HTML] The antitumor activity screening of chemical constituents from Camellia nitidissima Chi

X Hou, H Du, R Yang, J Qi… - International …, 2018 - spandidos-publications.com
Chemotherapy is the preferred and most common treatment for cancer in clinical practice.
An increasing number of researchers all over the world are focusing on natural medicines to …

[HTML][HTML] Phytochemical Profiling, Anti-Inflammatory, Anti-Oxidant and In-Silico Approach of Cornus macrophylla Bioss (Bark)

A Khan, A Pervaiz, B Ansari, R Ullah, SMM Shah… - Molecules, 2022 - mdpi.com
The objective of the current study was to evaluate the phytochemical and pharmacological
potential of the Cornus macrophylla. C. macrophylla belongs to the family Cornaceae. It is …

In vitro anticancer, antioxidant and enzyme inhibitory potentials of endemic Cephalaria elazigensis var. purpurea with in silico studies

MK Erdogan, R Gundogdu, Y Yapar… - Journal of …, 2023 - Taylor & Francis
In this study, the therapeutic potential and phytochemical composition of ethanolic extract of
Cephalaria elazigensis var. purpurea (CE), an endemic species, were investigated. For this …

QSAR, action mechanism and molecular design of flavone and isoflavone derivatives with cytotoxicity against HeLa

SY Liao, JC Chen, L Qian, Y Shen, KC Zheng - European journal of …, 2008 - Elsevier
The quantitative structure–activity relationship (QSAR) of 32 flavone and isoflavone
derivatives with cytotoxicity expressed as pGC50, which is defined as the negative value of …

[HTML][HTML] Integrated approach for studying bioactive compounds from Cladosporium spp. against estrogen receptor alpha as breast cancer drug target

S Anandan, HG Gowtham, CS Shivakumara… - Scientific Reports, 2022 - nature.com
Cladosporium spp. have been reported for their great diversity of secondary metabolites
which represent as a prominent base material for verifying the biological activities. Several …

Cytotoxic activity evaluation and molecular docking study of phenolic derivatives from Achillea fragrantissima (Forssk.) growing in Egypt

BM Awad, ES Habib, AK Ibrahim, AS Wanas… - Medicinal Chemistry …, 2017 - Springer
Abstract Achillea fragrantissima (Forssk) Sch. Bip.(Asteraceae) is one of the most important
medicinal plant species in Egypt. Phytochemical investigation of the methanolic extract of A …

[HTML][HTML] Bioactivities from Marine Algae of the Genus Gracilaria

CLF De Almeida, HS Falcão, GRM Lima… - International journal of …, 2011 - mdpi.com
Seaweeds are an important source of bioactive metabolites for the pharmaceutical industry
in drug development. Many of these compounds are used to treat diseases like cancer …