Drug nanocarriers and functional nanoparticles: applications in cancer therapy

B Thierry - Current drug delivery, 2009 - ingentaconnect.com
Extending on recent progress in control of matter at the nanoscale, functional nanoparticles
and drug nanocarriers are being actively developed with the promise of improved delivery of …

Peptide ligand-modified nanomedicines for targeting cells at the tumor microenvironment

A David - Advanced drug delivery reviews, 2017 - Elsevier
Since their initial discovery more than 30 years ago, tumor-homing peptides have become
an increasingly useful tool for targeted delivery of therapeutic and diagnostic agents into …

Protein‐based Nanoparticles: from Drug Delivery to Imaging, Nanocatalysis and Protein Therapy

J Kaltbeitzel, PR Wich - Angewandte Chemie International …, 2023 - Wiley Online Library
Proteins and enzymes are versatile biomaterials for a wide range of medical applications
due to their high specificity for receptors and substrates, high degradability, low toxicity, and …

Cancer nanomedicine: from targeted delivery to combination therapy

X Xu, W Ho, X Zhang, N Bertrand… - Trends in molecular …, 2015 - cell.com
The advent of nanomedicine marks an unparalleled opportunity to advance the treatment of
various diseases, including cancer. The unique properties of nanoparticles (NPs), such as …

[HTML][HTML] Peptide-enabled targeted delivery systems for therapeutic applications

M Liu, X Fang, Y Yang, C Wang - Frontiers in bioengineering and …, 2021 - frontiersin.org
Receptor-targeting peptides have been extensively pursued for improving binding specificity
and effective accumulation of drugs at the site of interest, and have remained challenging for …

Biotechnological approaches toward nanoparticle biofunctionalization

S Avvakumova, M Colombo, P Tortora… - Trends in …, 2014 - cell.com
Nanomedicine has emerged in the past decade as a promising tool for several therapeutic
and diagnostic applications. The development of nanoconjugates containing bioactive …

Tailoring nanocarriers for intracellular protein delivery

Z Gu, A Biswas, M Zhao, Y Tang - Chemical Society Reviews, 2011 - pubs.rsc.org
Proteins play a crucial role in life, taking part in all vital processes in the body. In the past
decade, there was increasing interest in delivering active forms of proteins to specific cells …

Albumin nanoparticles surface decorated with a tumor-homing peptide help in selective killing of triple-negative breast cancer cells

S Pal, FP Mohny, SG Choudhury… - … Applied Materials & …, 2023 - ACS Publications
In this article, we describe a method of delivery of doxorubicin using a novel tumor-homing
peptide-based albumin nanoparticle system to triple-negative breast cancer cells (TNBC) …

Intracellular delivery of proteins by nanocarriers

M Ray, YW Lee, F Scaletti, R Yu, VM Rotello - Nanomedicine, 2017 - Taylor & Francis
Intracellular delivery of proteins is potentially a game-changing approach for therapeutics.
However, for most applications, the protein needs to access the cytosol to be effective. A …

Recent advances in biocompatible nanocarriers for delivery of chemotherapeutic cargoes towards cancer therapy

CY Ang, SY Tan, Y Zhao - Organic & biomolecular chemistry, 2014 - pubs.rsc.org
Cancer is currently one of the major diseases that has gained a lot of scientific attention.
Conventional cancer therapeutics involve surgical removal of tumors from patients followed …