Pancreatic cancer: why is it so hard to treat?
PE Oberstein, KP Olive - Therapeutic advances in …, 2013 - journals.sagepub.com
No common malignancy is as rapidly and inevitably fatal as pancreatic ductal
adenocarcinoma (PDA). This grim fact has driven substantial research efforts into this …
adenocarcinoma (PDA). This grim fact has driven substantial research efforts into this …
The current treatment paradigm for pancreatic ductal adenocarcinoma and barriers to therapeutic efficacy
DR Principe, PW Underwood, M Korc… - Frontiers in …, 2021 - frontiersin.org
Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis, with a median survival
time of 10-12 months. Clinically, these poor outcomes are attributed to several factors …
time of 10-12 months. Clinically, these poor outcomes are attributed to several factors …
Pancreatic cancer: a review
CS Yabar, JM Winter - Gastroenterology Clinics, 2016 - gastro.theclinics.com
Pancreatic ductal adenocarcinoma (PDA) is the 12th most common cancer in the United
States. As of January 7, 2016, the American Cancer Society reported that pancreatic cancer …
States. As of January 7, 2016, the American Cancer Society reported that pancreatic cancer …
Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma
AJ Grossberg, LC Chu, CR Deig… - CA: a cancer journal …, 2020 - Wiley Online Library
Despite tremendous gains in the molecular understanding of exocrine pancreatic cancer,
the prognosis for this disease remains very poor, largely because of delayed disease …
the prognosis for this disease remains very poor, largely because of delayed disease …
Pancreatic cancer: a review
W Park, A Chawla, EM O'Reilly - Jama, 2021 - jamanetwork.com
Importance Pancreatic ductal adenocarcinoma (PDAC) is a relatively uncommon cancer,
with approximately 60 430 new diagnoses expected in 2021 in the US. The incidence of …
with approximately 60 430 new diagnoses expected in 2021 in the US. The incidence of …
Stromal biology and therapy in pancreatic cancer: a changing paradigm
A Neesse, H Algül, DA Tuveson, TM Gress - Gut, 2015 - gut.bmj.com
Pancreatic ductal adenocarcinoma (PDA) exhibits one of the poorest prognosis of all solid
tumours and poses an unsolved problem in cancer medicine. Despite the recent success of …
tumours and poses an unsolved problem in cancer medicine. Despite the recent success of …
Therapeutic trends in pancreatic ductal adenocarcinoma (PDAC)
S Chandana, HM Babiker… - Expert Opinion on …, 2019 - Taylor & Francis
Introduction: Prognosis remains dismal for pancreatic ductal adenocarcinoma (PDAC).
Genomics and proteomics have depicted heterogeneity in PDAC. Collectively, this …
Genomics and proteomics have depicted heterogeneity in PDAC. Collectively, this …
Translational therapeutic opportunities in ductal adenocarcinoma of the pancreas
M Hidalgo, DD Von Hoff - Clinical Cancer Research, 2012 - AACR
Pancreatic ductal adenocarcinoma (PDA) remains a devastating disease with nearly equal
incidence and mortality rates. Over the past few decades, a litany of randomized clinical …
incidence and mortality rates. Over the past few decades, a litany of randomized clinical …
Consensus report of the national cancer institute clinical trials planning meeting on pancreas cancer treatment
PA Philip, M Mooney, D Jaffe, G Eckhardt… - Journal of Clinical …, 2009 - ascopubs.org
Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer mortality,
despite significant improvements in diagnostic imaging and operative mortality rates. The 5 …
despite significant improvements in diagnostic imaging and operative mortality rates. The 5 …
Pancreatic cancer: from bench to 5-year survival
J Kleeff, C Michalski, H Friess, MW Büchler - Pancreas, 2006 - journals.lww.com
Pancreatic ductal adenocarcinoma is one of the most aggressive human malignancies, with
an overall 5-year survival rate of less than 4%. On the molecular level, an increasing number …
an overall 5-year survival rate of less than 4%. On the molecular level, an increasing number …