Temporomandibular joint disorder (TMD) is a complex musculoskeletal disorder that
presents with pain, limited jaw opening, and abnormal noises in the temporomandibular …

Aims: To use 2 well-characterized stimuli, the intraoral capsaicin model and the" nociceptive-
specific" electrode, to compare superficial nociceptive function between patients with …

Background/purpose The prevalence of orofacial pain is high but the etiology of orofacial
pain is not well understood. Because of clinical treatment is not so effective, it is urgent to …

Repeated application of capsaicin on the tongue has been used as a human oral pain
model to assess topical anesthetic–analgesic drugs. The reliability of the model was …

Aim: To examine, in a double-blind and placebo-controlled crossover manner, the effect of
topical application of capsaicin on the alveolar mucosa with a battery of intraoral quantitative …

Background Deficient endogenous pain modulation has been implicated in the development
and exacerbation of chronic orofacial pain. To date, relatively little is known regarding the …

Aims: To determine whether mucosal pain, evoked through a novel topical capsaicin model,
has an effect on jaw movement and whether psychologic factors have an association with …

Aims: To assess the spatial and temporal sensory effects of the topical application of
capsaicin and menthol on the gingiva of healthy volunteers. Methods: Capsaicin, menthol …

Chronic primary orofacial pain (OFP) conditions such as painful temporomandibular
disorders (pTMDs; ie, myofascial pain and arthralgia), idiopathic trigeminal neuralgia (TN) …

Aims: To investigate the predictive power of depression and anxiety for conditioned pain
modulation (CPM) and to examine the relationships of CPM at 40 C and CPM at 47 C with …