Capsaicin-induced burning sensation in the oral mucosa can be relieved by skimmed and
whole milk. The mechanism behind this effect, however, is unknown. This study aimed to …

Humans vary in oral pain tolerance. Our earlier studies noted that the responses of subjects
show 1 of 3 qualitative response patterns to a single oral capsaicin concentration, which we …

As burning mouth syndrome (BMS) and atypical odontalgia (AO) continue to remain
complex in terms of pathophysiology and lack explicit treatment protocol, clinicians are left …

The aims of this study were to investigate possible sex differences in (a) intraoral pain
evoked by topical application of capsaicin to the gingiva, and (b) the modulation of this pain …

The aim of this study was to investigate temporal and spatial aspects of somatosensory
changes after topical application of capsaicin, menthol and local anesthetics (LA) on the …

Atypical odontalgia (AO) is an intraoral pain condition of currently unknown mechanisms. In
10 AO patients and 10 matched healthy controls, we examined the effect of intravenous …

Capsaicin (trans-8-methyl-N-vanilyl-6-nonenamide) is a unique alkaloid isolated from hot
chili peppers of the capsicum family. Capsaicin is an agonist of transient receptor potential …

Several orofacial painful conditions are influenced by gender-related factors, but no studies
are available with regard to Burning Mouth Syndrome (BMS). The present study aimed at …

Objectives: In this study, we investigated temporal summation of pain (TSP) profiles, pain
ratings and secondary hyperalgesia responses in responders and nonresponders to 1 …

Objective Burning mouth syndrome (BMS) is an intractable chronic pain disorder
characterized by a burning sensation without organic abnormalities in the oral mucosa …