Plasma IL‐8 signature correlates with pain and depressive symptomatology in patients with burning mouth syndrome: Results from a pilot study

A Barry, KD O'Halloran, JP McKenna… - Journal of Oral …, 2018 - Wiley Online Library
Background Burning mouth syndrome (BMS) is a neuropathic orofacial pain condition of
unknown aetiology that encompasses intra‐oral burning pain without abnormal clinical …

Inducible desensitization to capsaicin with repeated low-dose exposure in human volunteers

AA Nolden, G Lenart, AI Spielman, JE Hayes - Physiology & Behavior, 2024 - Elsevier
Responses to capsaicin are reduced following repeated exposure, a phenomenon known
as capsaicin desensitization. Heavy consumers of chilies consistently report reduced oral …

[PDF][PDF] Orofacial pain conditions–pain and oral mucosa

AML Pedersen, H Forssell, B Grinde - pain, 2016 - utupub.fi
Pain of the oral mucosa is a common accompanying symptom of various oral mucosal
lesions caused by local and systemic diseases. Pain of the oral mucosa is usually …

The nocebo effect might affect treatment expectations in patients with burning mouth syndrome

EM Varoni, G Lodi, A Sardella - Pain, 2015 - journals.lww.com
The results of a recent and very interesting meta-analysis by Petersen et al. 7 open to
discussion of the extent of the nocebo effect in pain, and the importance of minimizing this …

Offset analgesia is increased intra‐orally

TM Szikszay, JLM Lévénez… - Journal of Oral …, 2022 - Wiley Online Library
Background Offset analgesia (OA) is commonly used to quantify endogenous pain inhibition.
However, the potential role of afferent inputs and the subsequent peripheral factors from …

Two-hit theory by estrogen in burning mouth syndrome

T Nagamine - Journal of Dental Sciences, 2022 - ncbi.nlm.nih.gov
Burning mouth syndrome (BMS) is characterized by chronic burning pain in a normal-
appearing oral mucosa. An important implication regarding the mechanism of pathogenesis …

Neuropathic pain in patients with burning mouth syndrome evaluated using painDETECT

P Lopez-Jornet, D Molino-Pagan, P Parra-Perez… - Pain …, 2017 - academic.oup.com
Objective. This study set out to identify the neuropathic component of pain experienced by
burning mouth syndrome (BMS) patients evaluated using painDETECT, a diagnostic tool …

Smell and taste dissociations in the modulation of tonic pain perception induced by a capsaicin cream application

MP Cecchini, M Riello, A Sandri, A Zanini… - … Journal of Pain, 2020 - Wiley Online Library
Background Pain is a subjective experience characterized by sensory (intensity) and
emotional (unpleasantness) aspects. Although literature reports behavioural effects on pain …

Burning mouth syndrome as a trigeminal small fibre neuropathy: Increased heat and capsaicin receptor TRPV1 in nerve fibres correlates with pain score

Z Yilmaz, T Renton, Y Yiangou, J Zakrzewska… - Journal of Clinical …, 2007 - Elsevier
Burning mouth syndrome (BMS) is often an idiopathic chronic and intractable pain condition,
affecting 1.5–5.5% of middle-aged and elderly women. We have studied the heat and …

Assessing regional sensitivity and desensitization to capsaicin among oral cavity mucosae

DN Berry, CT Simons - Chemical Senses, 2020 - academic.oup.com
This study aimed to determine perceptual response differences and characterize
desensitization to capsaicin over time across several oral cavity mucosae–the tongue …