The induction of angiogenesis and the promotion of tumor growth and invasiveness are
processes critical to metastasis, and are dependent on reciprocal interactions between …

Angiogenesis is now well known for being involved in tumor progression, aggressiveness,
emergence of metastases, and also resistance to cancer therapies. In this study, to better …

Angiogenesis marks the transformation of a benign local tumor into a life‐threatening
disease. Many in vitro assays are available on two‐dimensional (2D) platforms, however …

Tumor angiogenesis is controlled by the integrated action of physicochemical and biological
cues; however, the individual contributions of these cues are not well understood. We have …

Cell–microenvironment interactions play a critical role in the transformation of normal cells
into cancer; however, the underlying mechanisms and effects are far from being well …

The tumor microenvironment is a key factor in the progression and metastasis of cancer, the
complexity of which is not reproducible using two-dimensional (2D) culture models. While …

Three-dimensional culture alters cancer cell signaling; however, the underlying mechanisms
and importance of these changes on tumor vascularization remain unclear. A hydrogel …

The tumour microenvironment and tumour angiogenesis play a critical role in the
development and therapy of many cancers, but in vitro models reflecting these …

The development of high-throughput anticancer drug screening methods using patient-
derived cancer cell (PDC) lines that maintain their original characteristics in an in vitro three …

To ensure nutrient and oxygen supply, tumors beyond a size of 1–2 mm3 need a connection
to the vascular system. Thus, tumor cells modify physiological tissue homeostasis by …