Botulinum neurotoxin type A counteracts neuropathic pain and facilitates functional recovery after peripheral nerve injury in animal models
S Marinelli, S Luvisetto, S Cobianchi, W Makuch… - Neuroscience, 2010 - Elsevier
A growing interest was recently focused on the use of Botulinum neurotoxin serotype A
(BoNT/A) for fighting pain. The aim of this study was to investigate the effects of BoNT/A on …
(BoNT/A) for fighting pain. The aim of this study was to investigate the effects of BoNT/A on …
Anti-allodynic efficacy of botulinum neurotoxin A in a model of neuropathic pain
S Luvisetto, S Marinelli, S Cobianchi, F Pavone - Neuroscience, 2007 - Elsevier
Neuropathic pain is typified by injuries to the peripheral and central nervous system and
derives from such causes as cancer, diabetes, multiple sclerosis, post-herpetic neuralgia …
derives from such causes as cancer, diabetes, multiple sclerosis, post-herpetic neuralgia …
Botulinum toxin B affects neuropathic pain but not functional recovery after peripheral nerve injury in a mouse model
A Finocchiaro, S Marinelli, F De Angelis, V Vacca… - Toxins, 2018 - mdpi.com
Clinical use of neurotoxins from Clostridium botulinum is well established and is
continuously expanding, including in treatment of pain conditions. Background: The …
continuously expanding, including in treatment of pain conditions. Background: The …
Participation of pro-and anti-nociceptive interleukins in botulinum toxin A-induced analgesia in a rat model of neuropathic pain
M Zychowska, E Rojewska, W Makuch… - European journal of …, 2016 - Elsevier
Botulinum neurotoxin serotype A (BoNT/A) shows antinociceptive properties, and its clinical
applications in pain therapy are continuously increasing. BoNT/A specifically cleaves SNAP …
applications in pain therapy are continuously increasing. BoNT/A specifically cleaves SNAP …
Botulinum neurotoxin A enhances the analgesic effects on inflammatory pain and antagonizes tolerance induced by morphine in mice
V Vacca, S Marinelli, C Eleuteri, S Luvisetto… - Brain, Behavior, and …, 2012 - Elsevier
Over the recent years compelling evidence has accumulated indicating that botulinum
neurotoxin serotype A (BoNT/A) results in analgesic effects on neuropathic as well as …
neurotoxin serotype A (BoNT/A) results in analgesic effects on neuropathic as well as …
Botulinum toxin A, brain and pain
I Matak, Z Lacković - Progress in neurobiology, 2014 - Elsevier
Botulinum neurotoxin type A (BoNT/A) is one of the most potent toxins known and a potential
biological threat. At the same time, it is among the most widely used therapeutic proteins …
biological threat. At the same time, it is among the most widely used therapeutic proteins …
Botulinum neurotoxin A promotes functional recovery after peripheral nerve injury by increasing regeneration of myelinated fibers
S Cobianchi, J Jaramillo, S Luvisetto, F Pavone… - Neuroscience, 2017 - Elsevier
The injection of safe doses of botulinum neurotoxin A (BoNT/A) have been reported to be
useful for the treatment of neuropathic pain, but it is still unknown how functional recovery is …
useful for the treatment of neuropathic pain, but it is still unknown how functional recovery is …
Botulinum neurotoxin for pain management: insights from animal models
F Pavone, S Luvisetto - Toxins, 2010 - mdpi.com
The action of botulinum neurotoxins (BoNTs) at the neuromuscular junction has been
extensively investigated and knowledge gained in this field laid the foundation for the use of …
extensively investigated and knowledge gained in this field laid the foundation for the use of …
Bilateral analgesic effects of abobotulinumtoxinA (Dysport®) following unilateral administration in the rat
C Favre‐Guilmard, PE Chabrier… - European Journal of …, 2017 - Wiley Online Library
Background In addition to inhibition of muscle and glandular hyperactivity, botulinum
neurotoxin (Bo NT) type A also interferes with pain processing. Previously, in a rat model of …
neurotoxin (Bo NT) type A also interferes with pain processing. Previously, in a rat model of …
Do botulinum toxins have a role in the management of neuropathic pain?: a focused review
GE Francisco, H Tan, M Green - American Journal of Physical …, 2012 - journals.lww.com
Botulinum neurotoxin (BoNT) is usually used in physiatric practice in the treatment of
spasticity and dystonia. Research involving both animal and human subjects has emerged …
spasticity and dystonia. Research involving both animal and human subjects has emerged …