[HTML][HTML] DNA methylation in the pathogenesis of polycystic ovary syndrome

ER Vázquez-Martínez, YI Gómez-Viais… - …, 2019 - rep.bioscientifica.com
Polycystic ovary syndrome (PCOS) is the leading endocrine and metabolic disorder in
premenopausal women characterized by hyperandrogenism and abnormal development of …

[HTML][HTML] DNA methylation in polycystic ovary syndrome: emerging evidence and challenges

YN Liu, Y Qin, B Wu, H Peng, M Li, H Luo… - Reproductive Toxicology, 2022 - Elsevier
Polycystic ovary syndrome (PCOS) is a disease related to reproductive endocrine
abnormalities in women of reproductive age, often accompanied by metabolic diseases …

Role of genomic DNA methylation in PCOS pathogenesis: a systematic review and meta-analysis involving case-controlled clinical studies

K Rawat, A Sandhu, V Gautam… - Molecular Human …, 2022 - academic.oup.com
Polycystic ovary syndrome (PCOS) is often associated with aberrant DNA methylation.
Despite the advances in diagnostics and treatment of PCOS, the pathophysiological …

[HTML][HTML] Genome-wide screen of ovary-specific DNA methylation in polycystic ovary syndrome

YY Yu, CX Sun, YK Liu, Y Li, L Wang, W Zhang - Fertility and sterility, 2015 - Elsevier
Objective To compare genome-wide DNA methylation profiles in ovary tissue from women
with polycystic ovary syndrome (PCOS) and healthy controls. Design Case-control study …

[HTML][HTML] Characterization of DNA methylation and screening of epigenetic markers in polycystic ovary syndrome

P Cao, W Yang, P Wang, X Li… - Frontiers in cell and …, 2021 - frontiersin.org
Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine and metabolic disorder in
women, which is characterized by androgen excess, ovulation dysfunction, and polycystic …

[HTML][HTML] Genome-wide DNA methylation and gene expression patterns provide insight into polycystic ovary syndrome development

XX Wang, JZ Wei, J Jiao, SY Jiang, DH Yu, D Li - Oncotarget, 2014 - ncbi.nlm.nih.gov
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in
women. However, the epigenetic mechanism involved in PCOS progression remains largely …

[HTML][HTML] DNA methylome profiling of granulosa cells reveals altered methylation in genes regulating vital ovarian functions in polycystic ovary syndrome

P Sagvekar, P Kumar, V Mangoli, S Desai… - Clinical …, 2019 - Springer
Background Women with polycystic ovary syndrome (PCOS) manifest a host of ovarian
defects like impaired folliculogenesis, anovulation, and poor oocyte quality, which grossly …

Epigenetics of polycystic ovary syndrome

CF Concha, SE Recabarren, BF Pérez - Revista medica de Chile, 2017 - europepmc.org
Polycystic ovarian syndrome (PCOS) is an endocrine and metabolic dysfunction, highly
prevalent in women in their reproductive years. Hyperandrogenism, oligo-ovulation …

The epigenomics of polycystic ovarian syndrome: from pathogenesis to clinical manifestations

S Li, D Zhu, H Duan, Q Tan - Gynecological Endocrinology, 2016 - Taylor & Francis
Polycystic ovarian syndrome (PCOS) is a complex condition of ovarian dysfunction and
metabolic abnormalities with widely varying clinical manifestations resulting from …

[HTML][HTML] Polycystic ovary syndrome is transmitted via a transgenerational epigenetic process

NEH Mimouni, I Paiva, AL Barbotin, FE Timzoura… - Cell metabolism, 2021 - cell.com
Polycystic ovary syndrome (PCOS) is the most common reproductive and metabolic disorder
affecting women of reproductive age. PCOS has a strong heritable component, but its …