Identification and characterization of tunneling nanotubes for intercellular trafficking

S Abounit, E Delage, C Zurzolo - Current protocols in cell …, 2015 - Wiley Online Library
Tunneling nanotubes (TNTs) are thin membranous channels providing direct cytoplasmic
connection between remote cells. They are commonly observed in different cell cultures and …

Peering into tunneling nanotubes—The path forward

D Cordero Cervantes, C Zurzolo - The EMBO journal, 2021 - embopress.org
Abstract The identification of Tunneling Nanotubes (TNTs) and TNT‐like structures signified
a critical turning point in the field of cell‐cell communication. With hypothesized roles in …

Emerging physiological and pathological implications of tunneling nanotubes formation between cells

S Sisakhtnezhad, L Khosravi - European journal of cell biology, 2015 - Elsevier
Cell-to-cell communication is a critical requirement to coordinate behaviors of the cells in a
community and thereby achieve tissue homeostasis and conservation of the multicellular …

[HTML][HTML] The art of cellular communication: tunneling nanotubes bridge the divide

S Gurke, JFV Barroso, HH Gerdes - Histochemistry and cell biology, 2008 - Springer
The ability of cells to receive, process, and respond to information is essential for a variety of
biological processes. This is true for the simplest single cell entity as it is for the highly …

[HTML][HTML] Tunneling nanotubes: Reshaping connectivity

C Zurzolo - Current opinion in cell biology, 2021 - Elsevier
Tunneling nanotubes (TNTs), open membranous channels between connected cells,
represent a novel direct way of communication between distant cells for the diffusion of …

Cell communication by tunneling nanotubes: Implications in disease and therapeutic applications

R Mittal, E Karhu, JS Wang, S Delgado… - Journal of cellular …, 2019 - Wiley Online Library
Intercellular communication is essential for the development and maintenance of
multicellular organisms. Tunneling nanotubes (TNTs) are a recently recognized means of …

Tunneling nanotubes: Diversity in morphology and structure

MW Austefjord, HH Gerdes, X Wang - Communicative & integrative …, 2014 - Taylor & Francis
Tunneling nanotubes (TNTs) are recently discovered thin membranous tubes that
interconnect cells. During the last decade, research has shown TNTs to be diverse in …

Wiring through tunneling nanotubes–from electrical signals to organelle transfer

S Abounit, C Zurzolo - Journal of cell science, 2012 - journals.biologists.com
Tunneling nanotubes (TNTs) represent a subset of F-actin-based transient tubular
connections that allow direct communication between distant cells. Recent studies have …

[HTML][HTML] Opportunities and challenges in tunneling nanotubes research: how far from clinical application?

X Han, X Wang - International journal of molecular sciences, 2021 - mdpi.com
Tunneling nanotubes (TNTs) are recognized long membrane nanotubes connecting
distance cells. In the last decade, growing evidence has shown that these subcellular …

[HTML][HTML] Selective block of tunneling nanotube (TNT) formation inhibits intercellular organelle transfer between PC12 cells

NV Bukoreshtliev, X Wang, E Hodneland, S Gurke… - FEBS letters, 2009 - Elsevier
Organelle exchange between cells via tunneling nanotubes (TNTs) is a recently described
form of intercellular communication. Here, we show that the selective elimination of filopodia …