Time-of-flight secondary ion mass spectrometry (TOF-SIMS) using buckminsterfullerene
(C60) as the primary ion source has the ability to generate chemical images of surfaces with …

Time-of-flight secondary ion mass spectrometry (ToF-SIMS) provides a method for the
detection of native and exogenous compounds in biological samples on a cellular scale …

Time-of-flight secondary ion mass spectrometry (TOF-SIMS) has unique capabilities in the
area of high-resolution mass spectrometric imaging of biological samples. The technique …

Secondary ion mass spectrometry (SIMS) has seen increased application for high spatial
resolution chemical imaging of complex biological surfaces. The advent and commercial …

Time‐of‐flight secondary ion mass spectrometry (ToFSIMS) is being applied increasingly to
the study of biological systems where the chemical specificity of mass spectrometry and the …

Recent developments in desorption/ionisation mass spectrometry techniques have made
their application to biological analysis a realistic and successful proposition. Developments …

Investigation of the spatial distribution of lipids in cell membranes can lead to an improved
understanding of the role of lipids in biological function and disease. Time-of-flight …

In this study, a non-native chemical species, bromodeoxyuridine (BrdU), was imaged within
single HeLa cells using time-of-flight secondary ion mass spectrometry (TOF-SIMS). z …

Time-of-flight secondary ion mass spectrometry (TOF-SIMS) can be utilized to map the
distribution of various molecules on a surface with submicrometer resolution. Much of its …

A hybrid quadrupole orthogonal time-of-flight mass spectrometer optimized for matrix-
assisted laser desorption ionization (MALDI) and electrospray ionization has been equipped …