Aldosterone stimulation by angiotensin II: influence of gender, plasma renin, and familial resemblance

M Giacché, A Vuagnat, SC Hunt, PN Hopkins… - …, 2000 - Am Heart Assoc
The aldosterone response to infused angiotensin II (Ang II) in patients receiving a low-salt
diet has been described as an important phenotype for genetic studies on human …

Blunted aldosterone responsiveness to angiotensin II in normotensive subjects with familial predisposition to essential hypertension

C Beretta-Piccoli, C Pusterla, P Städler… - Journal of …, 1988 - journals.lww.com
The responsiveness of plasma aldosterone to an angiotensin (Ang) II infusion was assessed
in normotensive young men, nine without and 13 with a family history of essential …

Age, gender, and non-modulation: a sexual dimorphism in essential hypertension

NDL Fisher, C Ferri, C Bellini, A Santucci… - …, 1997 - Am Heart Assoc
The angiotensinogen gene is one of the very few related by linkage analysis to human
hypertension, but the linkage has been consistently shown only among males. Moreover …

Genetic determinants of nonmodulating hypertension

N Kosachunhanun, SC Hunt, PN Hopkins… - …, 2003 - Am Heart Assoc
We sought to determine whether genes of the renin-angiotensin-aldosterone system can
predict the nonmodulating intermediate phenotype in essential hypertension. Aldosterone …

Significance of angiotensinogen gene haplotypes and genotypes combinations in hypertension

A Nejatizadeh, R Kumar, T Stobdan… - Journal of …, 2008 - journals.lww.com
Objective Renin–angiotensin system gene polymorphisms are associated with essential
hypertension; angiotensinogen gene variants are considered potential genetic risk factors …

Altered aldosterone response to salt intake and angiotensin II infusion in young normotensive men with parental history of arterial hypertension

MP Schlaich, AU Klingbeil, J Jacobi… - Journal of …, 2002 - journals.lww.com
Objective An increased sensitivity to angiotensin II (Ang II) has been observed in patients
with established hypertension. In the current study we tested whether young normotensive …

Renin-angiotensin system genetic polymorphisms and salt sensitivity in essential hypertension

V Giner, E Poch, E Bragulat, J Oriola, D González… - …, 2000 - Am Heart Assoc
We evaluated the association between salt-sensitive hypertension and 3 different genetic
polymorphisms of the renin-angiotensin system. Fifty patients with essential hypertension …

Genetic determination of plasma aldosterone levels in essential hypertension

L Pojoga, S Gautier, H Blanc, TT Guyene… - American journal of …, 1998 - academic.oup.com
The renin-angiotensin-aldosterone system plays an important role in large artery structure
and blood pressure homeostasis. Among the genes coding for different components of this …

A gender difference in the association between salt sensitivity and family history of hypertension

K Shunichi, M Kazuo, K Genjiro, S Toru… - American journal of …, 1992 - academic.oup.com
There is increasing evidence that a major site of production of angiotensin I and II is
peripheral tissue. Both angiotensin I and II are present in venous blood in amounts far too …

1166 A/C polymorphism of the angiotensin II type 1 receptor gene and the response to short-term infusion of angiotensin II

KF Hilgers, MRW Langenfeld, M Schlaich, R Veelken… - Circulation, 1999 - Am Heart Assoc
Background—Previous studies reported an association of the 1166 A/C polymorphism of the
angiotensin II (Ang II) type 1 receptor gene with high blood pressure and cardiovascular …