The art of cellular communication: tunneling nanotubes bridge the divide

S Gurke, JFV Barroso, HH Gerdes - Histochemistry and cell biology, 2008 - Springer
The ability of cells to receive, process, and respond to information is essential for a variety of
biological processes. This is true for the simplest single cell entity as it is for the highly …

Peering into tunneling nanotubes—The path forward

D Cordero Cervantes, C Zurzolo - The EMBO journal, 2021 - embopress.org
Abstract The identification of Tunneling Nanotubes (TNTs) and TNT‐like structures signified
a critical turning point in the field of cell‐cell communication. With hypothesized roles in …

[HTML][HTML] Tunneling nanotubes: Reshaping connectivity

C Zurzolo - Current opinion in cell biology, 2021 - Elsevier
Tunneling nanotubes (TNTs), open membranous channels between connected cells,
represent a novel direct way of communication between distant cells for the diffusion of …

Identification and characterization of tunneling nanotubes for intercellular trafficking

S Abounit, E Delage, C Zurzolo - Current protocols in cell …, 2015 - Wiley Online Library
Tunneling nanotubes (TNTs) are thin membranous channels providing direct cytoplasmic
connection between remote cells. They are commonly observed in different cell cultures and …

Emerging physiological and pathological implications of tunneling nanotubes formation between cells

S Sisakhtnezhad, L Khosravi - European journal of cell biology, 2015 - Elsevier
Cell-to-cell communication is a critical requirement to coordinate behaviors of the cells in a
community and thereby achieve tissue homeostasis and conservation of the multicellular …

Multifaceted roles of tunneling nanotubes in intercellular communication

L Marzo, K Gousset, C Zurzolo - Frontiers in physiology, 2012 - frontiersin.org
Cell-to-cell communication and exchange of materials are vital processes in multicellular
organisms during cell development, cell repair, and cell survival. In neuronal and …

Wiring through tunneling nanotubes–from electrical signals to organelle transfer

S Abounit, C Zurzolo - Journal of cell science, 2012 - journals.biologists.com
Tunneling nanotubes (TNTs) represent a subset of F-actin-based transient tubular
connections that allow direct communication between distant cells. Recent studies have …

Cell communication by tunneling nanotubes: Implications in disease and therapeutic applications

R Mittal, E Karhu, JS Wang, S Delgado… - Journal of cellular …, 2019 - Wiley Online Library
Intercellular communication is essential for the development and maintenance of
multicellular organisms. Tunneling nanotubes (TNTs) are a recently recognized means of …

Intercellular transfer mediated by tunneling nanotubes

HH Gerdes, RN Carvalho - Current opinion in cell biology, 2008 - Elsevier
Animal cells have evolved different mechanisms to communicate with one another. In 2004,
a new route of cell-to-cell communication mediated by tunneling nanotubes (TNT) was …

[HTML][HTML] Long-distance electrical coupling via tunneling nanotubes

X Wang, HH Gerdes - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2012 - Elsevier
Tunneling nanotubes (TNTs) are nanoscaled, F-actin containing membrane tubes that
connect cells over several cell diameters. They facilitate the intercellular exchange of …