In the past years it was made a very huge effort to understand the genetic and molecular
signatures of glioblastoma in order to improve targeted molecular therapy: but to date …

Objective: The commonest class of BRAIN TUMOURS in adults are astrocytomas and the
commonest astrocytoma is the malignant GLIOBLASTOMA (GBM). Median life expectancy in …

Emerging evidence in the literature suggests the presence of a small subset of cells within
tumors, called cancer stem cells (CSCs), that drive tumor formation and growth and are …

Introduction: Human glioblastoma multiforme (GBM) represent the most frequent form of
primary brain tumors and is characterised by poor prognosis. Chemotherapeutic treatment is …

Glioblastoma is the most common type of primary brain tumor in adults and is among the
most lethal and least successfully treated solid tumors. Recently, research into the area of …

Glioblastoma (GBM) stem-like cells (GSCs) represent the most undifferentiated state of
malignant cells with distinct biological characteristics. The fraction of these cells within a glial …

Glioblastoma Multiforme (GBM) is the most frequent adult primary malignant brain tumor that
remains incurable despite aggressive treatment. The cell of origin (COO) for GBM is …

Background. Glioblastomas (GBM) are the most common, aggressive, and lethal malignant
brain tumor in adults. GBM Patients' median overall survival after the diagnosis does not …

Malignant gliomas are the most common type of primary brain tumor. In spite of huge
therapeutic efforts that include surgery, radiotherapy, and new alkylating agents, the disease …

Glioblastoma (GBM) is known to be the most common and lethal primary malignant brain
tumor. Therapies against this neoplasia have a high percentage of failure, associated with …