Background Vitamin D is crucial for maintenance of musculoskeletal health, and might also
have a role in extraskeletal tissues. Determinants of circulating 25-hydroxyvitamin D …

The primary circulating form of vitamin D, 25-hydroxy-vitamin D [25 (OH) D], is associated
with multiple medical outcomes, including rickets, osteoporosis, multiple sclerosis and …

Vitamin D insufficiency is common, correctable, and influenced by genetic factors, and it has
been associated with risk of several diseases. We sought to identify low-frequency genetic …

Vitamin D is implicated in a wide range of health outcomes, and although environmental
predictors of vitamin D levels are known, the genetic drivers of vitamin D status remain to be …

Context Lower serum 25-hydroxyvitamin D concentrations are associated with greater risks
of many chronic diseases across large, prospective community-based studies. Substrate 25 …

Vitamin D is a steroid hormone precursor that is associated with a range of human traits and
diseases. Previous GWAS of serum 25-hydroxyvitamin D concentrations have identified four …

Vitamin D deficiency is more common among African Americans (AAs) than among
European Americans (EAs), and epidemiologic evidence links vitamin D status to many …

We aimed to increase our understanding of the genetic determinants of vitamin D levels by
undertaking a large-scale genome-wide association study (GWAS) of serum 25 …

Vitamin D plays an essential role in human health as it influences immune function, cell
proliferation, differentiation and apoptosis. Vitamin D deficiency has been associated with …

Vitamin D plays several roles in the body, influencing bone health as well as serum calcium
and phosphate levels. Further, vitamin D may modify immune function, cell proliferation …