Intrathecal pramipexole and selegiline for sensory and motor block in rats

CC Yeh, CC Chiu, JJ Wang, AK Chou, YW Chen… - Pharmacological …, 2022 - Springer
Background The purpose of the study was to investigate spinal sensory and motor block by
antiparkinsonian drugs (pramipexole and selegiline), and the combination of pramipexole …

Intrathecal orphenadrine elicits spinal block in the rat

YW Chen, JI Tzeng, YC Chen, CH Hung… - European journal of …, 2014 - Elsevier
The purpose of this study was to estimate the local anesthetic effect of orphenadrine, an anti-
muscarinic agent, in spinal anesthesia and its comparison with the local anesthetic …

Intrathecal pramoxine causes long-lasting spinal sensory and motor block in rats

AK Chou, CC Chiu, MM Han, YW Chen… - Journal of Pharmacy …, 2018 - academic.oup.com
Objectives The objective of this experiment was to investigate spinal anaesthetic effects of
pramoxine and its comparison with bupivacaine, a long-lasting local anaesthetic. Methods …

Intrathecal chlorprothixene, cis (z)-flupenthixol, chlorpromazine and fluphenazine for prolonged spinal blockades of sensory and motor functions in rats

YW Chen, CC Chu, YC Chen, YM Leung… - European journal of …, 2012 - Elsevier
The aim of this study was to examine whether thioxanthine-type antipsychotics
(chlorprothixene and cis (z)-flupenthixol) and phenothiazine-type antipsychotics …

Isobolographic analysis of caramiphen and lidocaine on spinal anesthesia in rats

YW Chen, CC Chu, YC Chen, JJ Wang, CH Hung - Neuroscience letters, 2010 - Elsevier
The aims of the study were to evaluate the spinal anesthetic effect of caramiphen and also
assess spinal anesthetic interactions of caramiphen with lidocaine. Lidocaine, a common …

Intrathecal oxybuprocaine and proxymetacaine produced potent and long-lasting spinal anesthesia in rats

CH Hung, JJ Wang, YC Chen, CC Chu, YW Chen - Neuroscience letters, 2009 - Elsevier
Proxymetacaine and oxybuprocaine were clinically used for topical ocular anesthesia but
never for spinal anesthesia, and therefore spinal anesthetic effects of proxymetacaine and …

Chlorpheniramine produces spinal motor, proprioceptive and nociceptive blockades in rats

JI Tzeng, HT Lin, YW Chen, CH Hung… - European journal of …, 2015 - Elsevier
This study aimed to assess the local anesthetic effects of chlorpheniramine in spinal
anesthesia and is compared with mepivacaine, a widely-used local anesthetic. Spinal …

Isobolographic analysis of interaction between nisoxetine‐and mepivacaine‐induced spinal blockades in rats

YM Leung, CC Chu, CS Kuo, YW Chen… - Fundamental & …, 2014 - Wiley Online Library
Although nisoxetine has been shown to elicit cutaneous (peripheral) anesthesia, spinal
(central) anesthesia with nisoxetine was not exposed. The aim of this study was to examine …

Promazine and chlorpromazine for prolonged spinal anesthesia in rats

YW Chen, CC Chu, YC Chen, CD Kan, JJ Wang - Neuroscience Letters, 2012 - Elsevier
Though promazine and chlorpromazine elicited cutaneous anesthesia, no study of spinal
anesthesia with chlorpromazine and promazine has been reported. This study was to …

Ifenprodil for prolonged spinal blockades of motor function and nociception in rats

YW Chen, CC Chiu, JN Wang, CH Hung… - Pharmacological …, 2016 - Elsevier
Background The aim of the study was to compare the proposed spinal anesthetic effect of
ifenprodil, an a1 adrenergic receptor antagonist, with that of the long-acting local anesthetic …