We recently demonstrated that exposure to early life stress exacerbates nerve injury-
induced thermal and mechanical hypersensitivity in adult male and female mice …

Pain (nociceptive) input caudal to a spinal contusion injury increases tissue loss and impairs
long-term recovery. It was hypothesized that noxious stimulation has this effect because it …

Chronic pain after traumatic brain injury (TBI) is very common, but the mechanisms linking
TBI to pain experienced in the periphery have not been described. In this set of studies we …

Threat-induced pain modulation can increase survival by amplifying physiological and
behavioral reactions toward danger. Threat can also modulate spinal nociception …

High rates of acute and chronic pain are associated with traumatic brain injury (TBI), but
mechanisms responsible for the association remain elusive. Recent data suggest …

Hypermetabolism and anorexia are significant problems associated with major burn trauma.
Recent studies have implicated hypothalamic peptides and receptors of the corticotropin …

The exacerbation of musculoskeletal pain by stress in humans is modeled by the
musculoskeletal hyperalgesia in rodents following a forced swim. We hypothesized that …

Neuropathic pain is often accompanied by stress, anxiety and depression. Although there is
evidence for involvement of corticotropin‐releasing factor (CRF), the detailed neuronal basis …

Neuropathic pain (NP) is difficult to treat due to complex pathophysiological mechanisms.
Pulsed radiofrequency (RRF) has been used widely with neuromodulation effect in …

Neuropathic pain is difficult to treat in clinical practice, and the underlying mechanisms are
insufficiently elucidated. Previous studies have demonstrated that the neuronal Fc‐gamma …