Osteogenic sarcoma comprises less than 0.5 per cent of all cancers. Two brothers were
recently seen who were diagnosed as having osteogenic sarcoma approximately 28 months …

A brother and sister with osteogenic sarcoma are reported. A review of the literature reveals
thirty additional cases of osteogenic sarcoma in familial aggregation, sixteen of sibling …

We treated two cases of osteosarcoma in siblings. After intensive chemotherapy and
surgery, both patients are alive after 9 and 4 years without any signs of disease. We report …

The following report describes two consecutive brothers from a nonimmigrant family, with no
identifiable predisposing factors, who presented with osteosarcomas of their distal femurs …

1. The case histories of four siblings affected by osteogenic sarcoma are described. 2. The
lesions appeared over a period of twelve years. The ages of the patients at the onset of …

Discussion In an extensive search of the literature since 1935, we found thirteen case
reports ofosteosarcoma in siblings distnibuted among five families 369, In addition, Epstein …

Osteosarcoma is the most common primary malignancy of bone. Most cases are sporadic
without a known genetic or environmental cause. Heritable genetic predisposition …

Familial cancer is manifested by the early development of histologically different
malignancies in multiple members of a family at different anatomical sites. Two or more …

Studies to determine the etiology of osteosarcoma involve epidemiologic and environmental
factors and genetic impairments. Factors related to patient characteristics include age …

0 STEOGENIC sarcoma occurs most frequently in the second decade of life though it may
appear earlier or much later. It usually arises as a solitary growth at some site in the …