Prevention of chemotherapy-induced nausea and vomiting after high-dose melphalan and stem cell transplantation: review of the evidence and suggestions

A Tendas, F Marchesi, A Mengarelli, O Annibali… - Supportive Care in …, 2019 - Springer
Abstract Introduction High-dose melphalan (HDMel) is the most common conditioning
chemotherapy regimen for autologous stem cell transplantation (SCT) in patients affected by …

Chemotherapy-induced nausea and vomiting prophylaxis in high-dose melphalan and autologous stem cell transplantation

A Tendas, F Marchesi… - Clinical …, 2018 - clinical-lymphoma-myeloma …
We have read with great interest the paper by Trifilio and colleagues, 1 entitled “Olanzapine
Reduces Chemotherapy-induced Nausea and Vomiting Compared With Aprepitant in …

Evaluation of palonosetron, fosaprepitant, and olanzapine as antiemetic prophylaxis for fludarabine and melphalan-based conditioning regimens prior to allogeneic …

R Karpen, J Sen, S Wall, S Musson, J Tossey - Leukemia Research, 2024 - Elsevier
Background Limited data are available regarding efficacious antiemetic regimens to prevent
chemotherapy-induced nausea and vomiting (CINV) for patients undergoing allogeneic …

Olanzapine reduces chemotherapy-induced nausea and vomiting compared with aprepitant in myeloma patients receiving high-dose melphalan before stem cell …

S Trifilio, C Welles, K Seeger, S Mehta… - … Myeloma and Leukemia, 2017 - Elsevier
Introduction Acute and delayed chemotherapy-induced nausea and vomiting (CINV) occurs
in most patients who receive high-dose melphalan and significantly affects patients' quality …

Efficacy of aprepitant in preventing nausea and vomiting due to high-dose melphalan-based conditioning for allogeneic hematopoietic stem cell transplantation

M Sakurai, T Mori, J Kato, Y Koda, T Kikuchi… - International journal of …, 2014 - Springer
High-dose melphalan has been gaining recognition as a highly emetogenic agent used in
hematopoietic stem cell transplantation (HSCT). The aim of this retrospective study was to …

Clinical impact of aprepitant in patients receiving high-dose chemotherapy prior to autologous peripheral blood stem cell transplantation: a cost-effectiveness analysis

A Nakamura, Y Kojima, K Miyazawa, S Matsumoto… - Oncology, 2017 - karger.com
Objective: To evaluate the clinical and cost benefits of the administration of aprepitant for the
prophylaxis of chemotherapy-induced nausea and vomiting (CINV) during high-dose …

A triple-drug combination to prevent nausea and vomiting following BEAM chemotherapy before autologous hematopoietic stem cell transplantation

W Pielichowski, J Barzal, K Gawronski, B Mlot… - Transplantation …, 2011 - Elsevier
OBJECTIVE: We performed a clinical study of a triple-drug combination to evaluate its
efficacy to prevent both acute and delayed emesis after high-dose chemotherapy with BEAM …

Palonosetron, aprepitant, and dexamethasone for prevention of nausea and vomiting after high-dose melphalan in autologous transplantation for multiple myeloma: a …

A Isoda, R Saito, F Komatsu, Y Negishi… - International journal of …, 2017 - Springer
Chemotherapy-induced nausea and vomiting (CINV) is a significant side effect in multiple
myeloma (MM) patients receiving high-dose melphalan treatment followed by autologous …

Multiple-day administration of fosaprepitant combined with tropisetron and olanzapine improves the prevention of nausea and vomiting in patients receiving …

P Ye, R Pei, T Wang, J Cao, P Zhang, D Chen… - Annals of …, 2022 - Springer
Chemotherapy-induced nausea and vomiting (CINV) is common in patients with lymphoma
and multiple myeloma (MM) receiving high-dose chemotherapy (HDC) followed by …

Aprepitant, granisetron, and dexamethasone for prevention of chemotherapy-induced nausea and vomiting after high-dose melphalan in autologous transplantation …

T Schmitt, H Goldschmidt, K Neben… - Journal of Clinical …, 2014 - ascopubs.org
Purpose The optimal regimen to prevent chemotherapy-induced nausea and vomiting
(CINV) for patients undergoing high-dose chemotherapy and autologous stem-cell …