Long QT syndrome: Not just a ventricular problem

JR Skinner, NA Lever - Heart Rhythm, 2008 - heartrhythmjournal.com
The potassium and sodium ion channels defective in the long QT syndromes (LQTS) are
present in the atria as well as the ventricles, so atrial arrhythmias may be anticipated in …

Arrhythmogenic mechanisms of QT prolonging drugs: is QT prolongation really the problem?

C Antzelevitch - Journal of electrocardiology, 2004 - Elsevier
Torsade de Pointes (TdP) is an atypical ventricular arrhythmias associated with the acquired
and congenital forms of the long QT syndrome. The substrate for the arrhythmia develops as …

Pauses after burst pacing provoke afterdepolarizations and torsades de pointes in a patient with long QT syndrome

P Kirchhof, S Zellerhoff, G Mönnig, E Schulze-Bahr - Heart Rhythm, 2004 - Elsevier
A patient with long QT syndrome and syncope underwent electrophysiological testing and
recording of monophasic action potentials (MAP). Programmed ventricular stimulation using …

Experimental models of torsade de pointes

L Eckardt, W Haverkamp, M Borggrefe… - Cardiovascular …, 1998 - academic.oup.com
Torsade de pointes is a potentially life threatening form of polymorphic ventricular
tachycardia typically seen in the setting of congenital and acquired abnormal QT …

[PDF][PDF] Twisting of the points

R Lazzara - Journal of the American College of Cardiology, 1997 - core.ac.uk
The aggregation of the defining electrocardiographic features of the long QT syndromes
occupied a decade of observations collected by various observers scattered around the …

Electrophysiologic mechanisms of the long QT interval syndromes and torsade de pointes

HL Tan, CJY Hou, MR Lauer, RJ Sung - Annals of internal medicine, 1995 - acpjournals.org
Purpose: To review the current understanding of the mechanisms and treatment of the long
QT interval syndromes and torsade de pointes. Data Sources: Personal databases of the …

Congenital Long QT syndrome and torsade de pointes

N El‐Sherif, G Turitto, M Boutjdir - Annals of Noninvasive …, 2017 - Wiley Online Library
Since its initial description by Jervell and Lange‐Nielsen in 1957, the congenital long QT
syndrome (LQTS) has been the most investigated cardiac ion channelopathy. A prolonged …

Giant T–U waves precede torsades de pointes in long QT syndrome: a systematic electrocardiographic analysis in patients with acquired and congenital QT …

P Kirchhof, MR Franz, A Bardai, AM Wilde - Journal of the American College …, 2009 - jacc.org
Objectives: This study sought to identify electrocardiographic (ECG) criteria that are
associated with initiation of torsades de pointes (TdP) in patients with acquired (a-) and …

Torsade de pointes: the clinical considerations

RM Gowda, IA Khan, SL Wilbur, BC Vasavada… - International journal of …, 2004 - Elsevier
Torsade de pointes is a form of polymorphic ventricular tachycardia occurring in a setting of
prolonged QT interval on surface electrocardiogram. Congenital causes of prolonged QT …

Long QT syndrome misdiagnosed and mistreated as a seizure disorder for eight years

SN Khouzam, RN Khouzam - The Canadian Journal of Cardiology, 2009 - ncbi.nlm.nih.gov
The case of a 19-year-old girl who was treated since she was 11 years of age for what was
thought to be a seizure disorder is presented. Various anticonvulsants (carbamazepine …