Making molecules make themselves–the chemistry of artificial replicators
A Vidonne, D Philp - European Journal of Organic Chemistry, 2009 - Wiley Online Library
Examples of chemical systems capable of templating and catalyzing their own synthesis–so‐
called replicating systems–have begun to appear in the chemical literature over the last 20 …
called replicating systems–have begun to appear in the chemical literature over the last 20 …
Minimal self-replicating systems
A Robertson, AJ Sinclair, D Philp - Chemical Society Reviews, 2000 - pubs.rsc.org
Examples of chemical systems capable of templating and catalysing their own synthesis—
self-replicating systems—have begun to appear in the chemical literature over the last 15 …
self-replicating systems—have begun to appear in the chemical literature over the last 15 …
Existing Self‐Replicators Can Direct the Emergence of New Ones
The study of the interplay between different self‐replicating molecules constitutes an
important new phase in the synthesis of life and in unravelling the origin of life. Here we …
important new phase in the synthesis of life and in unravelling the origin of life. Here we …
[HTML][HTML] Towards open-ended evolution in self-replicating molecular systems
In this review we discuss systems of self-replicating molecules in the context of the origin of
life and the synthesis of de novo life. One of the important aspects of life is the ability to …
life and the synthesis of de novo life. One of the important aspects of life is the ability to …
Artificial replication systems
S Hoffmann - Angewandte Chemie International Edition in …, 1992 - Wiley Online Library
Replicative information systems were the signal for the departure of Evolution into its
biological phase and the leitmotiv for our scientific attempts at its imitation. This research …
biological phase and the leitmotiv for our scientific attempts at its imitation. This research …
[PDF][PDF] Self replicating systems
V Patzke, G von Kiedrowski - Arkivoc, 2007 - arkat-usa.org
Chemical self-replicating systems have been the subject of various investigations over the
last 20 years. This mini review outlines the design of minimal model systems, mainly based …
last 20 years. This mini review outlines the design of minimal model systems, mainly based …
Synthetic replicators and extrabiotic chemistry
TK Park, Q Feng, J Rebek Jr - Journal of the American Chemical …, 1992 - ACS Publications
Synthetic replicators can be generated by covalent attachment of two complementary
structures to form a selfcomplementary molecule. The complementarity refers to sizes …
structures to form a selfcomplementary molecule. The complementarity refers to sizes …
Emergence of a new self-replicator from a dynamic combinatorial library requires a specific pre-existing replicator
Our knowledge regarding the early steps in the formation of evolvable life and what
constitutes the minimal molecular basis of life remains far from complete. The recent …
constitutes the minimal molecular basis of life remains far from complete. The recent …
Chemical fueling enables molecular complexification of self‐replicators
Unravelling how the complexity of living systems can (have) emerge (d) from simple
chemical reactions is one of the grand challenges in contemporary science. Evolving …
chemical reactions is one of the grand challenges in contemporary science. Evolving …
Parasitic Behavior of Self‐Replicating Molecules
Self‐replication plays a central role in the origin of life and in strategies to synthesize life de
novo. Studies on self‐replication have focused mostly on isolated systems, while the …
novo. Studies on self‐replication have focused mostly on isolated systems, while the …