The two major types of IBD are ulcerative colitis (UC) and Crohn's disease (CD), whose
etiology involves immunological and environmental factors. CD and UC share some …

Abstract Background and Aim Interleukin (IL)-1 family members play an important role in the
pathogenesis of inflammatory bowel disease (IBD). There are conflicting results regarding …

Crohn's disease and ulcerative colitis are examples of inflammatory bowel disease (IBD),
and are multifaceted chronic autoimmune disorders with unknown etiology; to date, there is …

Through rapid advances, genome-wide association studies (GWAS) have identified almost
100 susceptibility genes which confer an increased risk of developing inflammatory bowel …

Objectives: It is aimed to determine the association between four single-nucleotide
polymorphisms (SNPs) of IL1 genes (rs1800587: IL1A− 889 C/T, rs16944: IL1B− 511 T/C …

Although the precise aetiology of inflammatory bowel disease (IBD) remains unclear, recent
discoveries have led to an improved understanding of disease pathogenesis. Whilst these …

Ulcerative colitis (UC) is one of the two subtypes of inflammatory bowel disease (IBD). UC is
a complex genetic disease that involves an abnormal immune response to the intestinal …

Crohn's disease and ulcerative colitis are chronic inflammatory disorders caused by a
disruptive interaction between the immune system and gut luminal factors. Although the …

Crohn's disease (CD) and ulcerative colitis (UC) are chronic inflammatory bowel diseases
(IBDs) occurring in the gut of genetically susceptible individuals independent of a specific …

Insights into the pathogenesis of inflammatory bowel diseases (IBDs) have provided
important information for the development of therapeutics. Levels of interleukin 23 (IL23) and …