The risk for congenital heart defects in offspring of individuals with congenital heart defects

O Romano‐Zelekha, R Hirsh, L Blieden… - Clinical …, 2001 - Wiley Online Library
Background: Congenital heart defects (CHDs) occur in approximately 1% of all live births.
Although most CHDs are of unknown etiology, a family history of CHDs is a known risk …

Risk of congenital heart defects in offspring of affected mothers and fathers

N Øyen, HA Boyd, L Carstensen… - Circulation: Genomic …, 2022 - Am Heart Assoc
Background: Smaller studies have reported a higher offspring risk of congenital heart
defects (CHDs) for mothers with CHDs than for fathers with CHDs. In a large population …

Recurrence of congenital heart defects among siblings—a nationwide study

K Brodwall, G Greve, E Leirgul, GS Tell… - American journal of …, 2017 - Wiley Online Library
Congenital heart defects (CHD) constitute the largest group of congenital malformations. In
most families, only one person has CHD; however, the risk of CHD increases for children …

Recurrence of congenital heart defects in families

N Øyen, G Poulsen, HA Boyd, J Wohlfahrt… - Circulation, 2009 - Am Heart Assoc
Background—Knowledge of the familial contribution to congenital heart diseases (CHD) on
an individual and population level is sparse. We estimated an individual's risk of CHD given …

Risk factors predisposing to congenital heart defects

FU Haq, F Jalil, S Hashmi, MI Jumani… - Annals of pediatric …, 2011 - journals.lww.com
Methods: A case-control study was done on pediatric patients at a tertiary care hospital, Aga
Khan University Hospital, located in Karachi, Pakistan. A total of 500 patients, 250 cases and …

Patterns, prevalence, risk factors, and survival of newborns with congenital heart defects in a Saudi population: a three-year, cohort case-control study

MA Majeed-Saidan, M Atiyah, AN Ammari… - Journal of Congenital …, 2019 - Springer
Background Congenital heart defects (CHD) are the most common types of birth defects.
The prevalence of CHD, mostly from retrospective studies, ranges between 2.1 and …

Consanguineous marriage and congenital heart defects: A case‐control study in the neonatal period

Y Khalid, M Ghina, B Fadi, C Fadi, K May… - American journal of …, 2006 - Wiley Online Library
The independent effect of consanguinity on the prevalence of congenital heart defects
(CHDs), all and specific types, was investigated in newborns admitted to nine hospitals …

Maternal age and prevalence of isolated congenital heart defects in an urban area of the United States

A Miller, T Riehle‐Colarusso, C Siffel… - American journal of …, 2011 - Wiley Online Library
Although maternal age has been associated with a number of birth defects in several
reports, the literature on the association of maternal age with isolated congenital heart defect …

Familial co-occurrence of congenital heart defects follows distinct patterns

SG Ellesøe, CT Workman, P Bouvagnet… - European heart …, 2018 - academic.oup.com
Aims Congenital heart defects (CHD) affect almost 1% of all live born children and the
number of adults with CHD is increasing. In families where CHD has occurred previously …

Familial risks of congenital heart defect assessed in a population‐based epidemiologic study

JA Boughman, KA Berg, JA Astemborski… - American journal of …, 1987 - Wiley Online Library
Congenital heart defects (CHD) represent a heterogeneous group of disorders caused by
chromosome abnormalities, mendelian disorders, teratogenic expo‐sures, and unknown …