Objectives Whole-genome sequencing (WGS) is rarely used for drug resistance testing of
Mycobacterium tuberculosis in high-endemic settings. Here we present the first study from …

Background Diagnosing drug-resistance remains an obstacle to the elimination of
tuberculosis. Phenotypic drug-susceptibility testing is slow and expensive, and commercial …

Objectives Our aim was to assess the ability of the Whole-genome sequencing (WGS) in
predicting drug resistance profile of multidrug-resistant mycobacterium tuberculosis (MDR …

Background Whole genome sequencing (WGS) has been proposed as a tool for diagnosing
drug resistance in tuberculosis. However, reports of its effectiveness in endemic countries …

Background Mycobacterium tuberculosis resistance to anti-tuberculosis drugs is a major
threat to global public health. Whole genome sequencing (WGS) is rapidly gaining traction …

Objectives We conducted a systematic review to determine the diagnostic accuracy of whole
genome sequencing (WGS) of Mycobacterium tuberculosis for the detection of resistance to …

Background Multidrug-resistant tuberculosis (MDR–TB) remains a major public health
problem in many high tuberculosis (TB) burden countries. Phenotypic drug susceptibility …

Tuberculosis (TB) is a global infectious threat that is intensified by an increasing incidence of
highly drug-resistant disease. Whole-genome sequencing (WGS) studies of Mycobacterium …

Amplification of drug resistance in Mycobacterium tuberculosis (M. tb) and its transmission
are significant barriers in controlling tuberculosis (TB) globally. Diagnostic inaccuracies and …

Whole-genome sequencing (WGS) has the potential to accelerate drug-susceptibility testing
(DST) to design appropriate regimens for drug-resistant tuberculosis (TB). Several recently …