The lymph node is a highly organized and dynamic structure that is critical for facilitating the
intercellular interactions that constitute adaptive immunity. Most ex vivo studies of the lymph …

The lymph node is a highly structured organ that mediates the body's adaptive immune
response to antigens and other foreign particles. Central to its function is the distinct spatial …

ABSTRACT A hallmark of the mammalian immune system is its ability to respond efficiently
to foreign antigens without eliciting an inappropriate response to self-antigens. Furthermore …

The lymphatic network that transports interstitial fluid and antigens to lymph nodes
constitutes a conduit system that can be hijacked by invading pathogens to achieve systemic …

The lymph node is a structurally complex organ of the immune system, whose dynamic
cellular arrangements are thought to control much of human health. Currently, no methods …

Lymph nodes (LNs) are organs of the immune system, critical for maintenance of
homeostasis and initiation of immune responses, yet there are few models that accurately …

The interaction of immune cells with drugs and/or with other cell types should be
mechanistically investigated in order to reduce attrition of new drug development. However …

Lymph nodes (LNs) comprise two main structural elements: fibroblastic reticular cells that
form dedicated niches for immune cell interaction and capsular fibroblasts that build a shell …

Lymph nodes are secondary lymphoid organs in which immune responses of the adaptive
immune system are initiated and regulated. Distributed throughout the body and embedded …

Immune responses occur as a result of stochastic interactions between a plethora of different
cell types and molecules that regulate the migration and function of innate and adaptive …