[HTML][HTML] A neuroanatomical framework for upper limb synergies after stroke

AJC McMorland, KD Runnalls… - Frontiers in human …, 2015 - frontiersin.org
Muscle synergies describe common patterns of co-or reciprocal activation that occur during
movement. After stroke, these synergies change, often in stereotypical ways. The …

[HTML][HTML] Abnormal synergies and associated reactions post-hemiparetic stroke reflect muscle activation patterns of brainstem motor pathways

LM McPherson, JPA Dewald - Frontiers in neurology, 2022 - frontiersin.org
Individuals with moderate-to-severe post-stroke hemiparesis cannot control proximal and
distal joints of the arm independently because they are constrained to stereotypical …

[HTML][HTML] Cortex integrity relevance in muscle synergies in severe chronic stroke

E García-Cossio, D Broetz, N Birbaumer… - Frontiers in human …, 2014 - frontiersin.org
Background: Recent experimental evidence has indicated that the motor system coordinates
muscle activations through a linear combination of muscle synergies that are specified at the …

[HTML][HTML] Are movement disorders and sensorimotor injuries pathologic synergies? When normal multi-joint movement synergies become pathologic

M Santello, CE Lang - Frontiers in human neuroscience, 2015 - frontiersin.org
The intact nervous system has an exquisite ability to modulate the activity of multiple
muscles acting at one or more joints to produce an enormous range of actions. Seemingly …

Stability of muscle synergies for voluntary actions after cortical stroke in humans

VCK Cheung, L Piron, M Agostini… - Proceedings of the …, 2009 - National Acad Sciences
Production of voluntary movements relies critically on the functional integration of several
motor cortical areas, such as the primary motor cortex, and the spinal circuitries …

[HTML][HTML] Neuromodulatory inputs to motoneurons contribute to the loss of independent joint control in chronic moderate to severe hemiparetic stroke

JG McPherson, MD Ellis, RN Harden… - Frontiers in …, 2018 - frontiersin.org
In chronic hemiparetic stroke, increased shoulder abductor activity causes involuntary
increases in elbow, wrist, and finger flexor activation, an abnormal muscle coactivation …

Progressive recruitment of contralesional cortico‐reticulospinal pathways drives motor impairment post stroke

JG McPherson, A Chen, MD Ellis, J Yao… - The Journal of …, 2018 - Wiley Online Library
Key points Activation of the shoulder abductor muscles in the arm opposite a unilateral brain
injury causes involuntary increases in elbow, wrist and finger flexion in the same arm, a …

[HTML][HTML] Alterations of muscle synergies during voluntary arm reaching movement in subacute stroke survivors at different levels of impairment

B Pan, Y Sun, B Xie, Z Huang, J Wu, J Hou… - Frontiers in …, 2018 - frontiersin.org
Motor system uses muscle synergies as a modular organization to simplify the control of
movements. Motor cortical impairments, such as stroke and spinal cord injuries, disrupt the …

Muscle synergies: implications for clinical evaluation and rehabilitation of movement

S Safavynia, G Torres-Oviedo… - Topics in spinal cord …, 2011 - meridian.allenpress.com
We present a method called muscle synergy analysis, which can offer clinicians insight into
both underlying neural strategies for movement and functional outcomes of muscle activity …

Muscle synergy patterns as physiological markers of motor cortical damage

VCK Cheung, A Turolla, M Agostini… - Proceedings of the …, 2012 - National Acad Sciences
The experimental findings herein reported are aimed at gaining a perspective on the
complex neural events that follow lesions of the motor cortical areas. Cortical damage …