This review examines the place of mitochondria in the life cycle through oogenesis,
ovulation and early embryogenesis. Mitochondria are semi-autonomous organelles …

This review examines current understanding of mammalian mitochondria and mitochondrial
DNA in the light of new reproductive technologies. Mitochondria are central to ageing …

In addition to their role in generating energy (ATP), other possible regulatory functions for
mitochondria in the mature oocyte, preimplantation stage embryo and differentiating …

Mitochondria play a pivotal role in cellular metabolism and are important determinants of
embryonic development. Mitochondrial function and biogenesis rely on an intricate …

Purpose To evaluate the effect of mitochondrial transfer on embryonic development.
Materials and methods Mitochondria concentrates were collected from murine hepatocytes …

Our fascination for mitochondria relates to their origin as symbiotic, semi-independent
organisms on which we, as eukaryotic beings, rely nearly exclusively to produce energy for …

Mitochondria play a primary role in cellular energetic metabolism, homeostasis, and death.
They possess their own multicopy genome, which is maternally transmitted. Mitochondria …

Mitochondria have long been known to be the powerhouses of the cell but they also
contribute to redox and Ca 2+ homeostasis, provide intermediary metabolites and store …

Mitochondria are well known as 'the powerhouses of the cell'. Indeed, their major role is
cellular energy production driven by both mitochondrial and nuclear DNA. Such a feature …

The role of mitochondria as a nexus of developmental regulation in mammalian oogenesis
and early embryogenesis is emerging from basic research in model species and from …