Mitochondrial VDAC and hexokinase together modulate plant programmed cell death

A Godbole, AK Dubey, PS Reddy, M Udayakumar… - Protoplasma, 2013 - Springer
The voltage-dependent anion channel (VDAC) and mitochondrially located hexokinase
have been implicated both in pathways leading to cell death on the one hand, and …

Programmed cell death in plants: a role for mitochondrial-associated hexokinases

NA Eckardt - 2006 - academic.oup.com
''By the time I was born, more of me had died than survived. It was no wonder I cannot
remember; during that time I went through brain after brain for nine months, finally contriving …

[HTML][HTML] VDAC is a conserved element of death pathways in plant and animal systems

A Godbole, J Varghese, A Sarin, MK Mathew - Biochimica et Biophysica …, 2003 - Elsevier
Programmed cell death (PCD) is very much a part of plant life, although the underlying
mechanisms are not so well understood as in animals. In animal cells, the voltage …

The functions of voltage-dependent anion channels in plants

Y Takahashi, C Tateda - Apoptosis, 2013 - Springer
Voltage-dependent anion channels (VDACs), known as outer mitochondrial membrane
proteins, are present in all eukaryotic cells. In mammals, they are now recognized to play …

[HTML][HTML] Regulation of VDAC trafficking modulates cell death

AK Dubey, A Godbole, MK Mathew - Cell Death Discovery, 2016 - nature.com
The voltage-dependent anion channel (VDAC) and mitochondria-associated hexokinase
(HxK) have crucial roles in both cell survival and death. Both the individual abundances and …

Voltage-dependent anion channels: their roles in plant defense and cell death

T Kusano, C Tateda, T Berberich, Y Takahashi - Plant cell reports, 2009 - Springer
The voltage-dependent anion channels (VDACs), mitochondrial outer membrane
components, are present in organisms from fungi to animals and plants. They are thought to …

Viability of Saccharomyces cerevisiae cells following exposure to H2O2 and protective effect of minocycline depend on the presence of VDAC

H Gałgańska, A Karachitos, M Baranek… - European journal of …, 2010 - Elsevier
Proteins involved in apoptosis are still a matter of debate. Therefore, we decided to check
the effect of the presence of VDAC (voltage dependent anion selective channel) on viability …

Molecular and genetic characterization of the gene family encoding the voltage-dependent anion channel in Arabidopsis

C Tateda, K Watanabe, T Kusano… - … of experimental botany, 2011 - academic.oup.com
The voltage-dependent anion channel (VDAC), a major outer mitochondrial membrane
protein, is thought to play an important role in energy production and apoptotic cell death in …

In self-defence: hexokinase promotes voltage-dependent anion channel closure and prevents mitochondria-mediated apoptotic cell death

H Azoulay-Zohar, A Israelson, S Abu-Hamad… - Biochemical …, 2004 - portlandpress.com
In tumour cells, elevated levels of mitochondria-bound isoforms of hexokinase (HK-I and HK-
II) result in the evasion of apoptosis, thereby allowing the cells to continue proliferating. The …

[HTML][HTML] Hexokinase-I protection against apoptotic cell death is mediated via interaction with the voltage-dependent anion channel-1: mapping the site of binding

S Abu-Hamad, H Zaid, A Israelson, E Nahon… - Journal of Biological …, 2008 - ASBMB
In brain and tumor cells, the hexokinase isoforms HK-I and HK-II bind to the voltage-
dependent anion channel (VDAC) in the outer mitochondrial membrane. We have …