Background Retinoblastoma is a highly malignant tumor of the eye that manifests most often
in the first 3 years of life. Methods Published articles were reviewed to evaluate the clinical …

Treatment of retinoblastoma has undergone significant advancements over the past few
decades, as globe-salvaging therapies with chemoreduction and focal consolidation are …

Retinoblastoma (Rb) is the most common primary intraocular malignancy of childhood, but
an uncommon paediatric cancer, with a constant incidence worldwide of 1: 15,000–1 …

Retinoblastoma represents approximately 4% of all pediatric malignancies and is the most
common primary intraocular cancer in children. 1, 2 Worldwide, it is estimated that there are …

Retinoblastoma is the most common intraocular cancer of childhood (Shields and Shields
2015; JA and CL 1992; Kivela 2009; Ramasubramanian and Shields 2012a). This …

Background Retinoblastoma is the most common primary intraocular malignancy in children.
The management of retinoblastoma is complex and depends on several factors. Methods …

Retinoblastoma can present in 1 or both eyes and is the most common intraocular
malignancy in childhood. It is typically initiated by biallelic mutation of the RB1 tumor …

Retinoblastoma is the most common intraocular malignancy in children. The survival of
retinoblastoma patients and visual outcome has improved dramatically in the developed …

Progressive advances in the understanding of retinoblastoma pathogenesis continue to lead
treatment strategies. Improvements in the diagnosis and management of retinoblastoma are …

PURPOSE: To provide an overview of the current clinical management of retinoblastoma by
discussing the trends in the categorization, treatment, and recent advances in molecular …