The intestinal tract, known for its capability for self-renew, represents the first barrier of
defence between the organism and its luminal environment. The thiol/disulfide redox …

The intestinal epithelium sits at the interface between an organism and its luminal
environment, and as such is prone to oxidative damage induced by luminal oxidants …

Redox signalling in the gastrointestinal mucosa is held in an intricate balance. Potent
microbicidal mechanisms can be used by infiltrating immune cells, such as neutrophils, to …

The unique anatomy and physiology of the intestine in conjunction with its microbial content
create the steepest oxygen gradients in the body, which plunge to near anoxia at the luminal …

Mucosal proliferation, together with differentiation and apoptosis, are a continuous
homeostatic process in the intestinal epithelium. The glutathione/glutathione disulfide redox …

The human gastrointestinal tract is home to a complex microbial community that plays an
important role in the general well-being of the entire organism. The gut microbiota generates …

Oxidative stress is thought to play a key role in the development of intestinal damage in
inflammatory bowel disease (IBD), because of its primary involvement in intestinal cells' …

Redox signaling regulates physiological self-renewal, proliferation, migration and
differentiation in gastrointestinal epithelium by modulating Wnt/β-catenin and Notch …

The microbiota that populates the intestinal tract affects many physiological processes, such
as cell proliferation, epithelial barrier function, and immune responses. However, the …

Gut epithelia and other cell types contacted by enteric commensal bacteria generate
reactive oxygen species (ROS) in response to microbial signals. Physiologically generated …