Objectives Age and female sex are risk factors for dementia, and menopause is associated
with cognitive dysfunction. Previous work largely considered the effects of sex and …

Background To date, there is no homogeneous evidence of whether earlier age at
menopause is associated with incident dementia. In addition, the underlying mechanism …

Objectives: To investigate the cross-sectional association between measures of
menstruation history (including menopausal status, age of menopause, age of menarche …

Background: Midlife obesity has been linked to age-related brain atrophy and risk of
dementia, but the relationships are less clear for older individuals. These associations may …

All women undergo the menopause transition (MT), a neuro-endocrinological process that
impacts aging trajectories of multiple organ systems including brain. The MT occurs over …

Sex hormones such as estrogen fluctuate across the female lifespan, with high levels during
reproductive years and natural decline during the transition to menopause. Women's …

Medial temporal lobe (MTL) atrophy is correlated with risk and severity of Alzheimer disease
(AD) pathology and cognitive decline. Increasing evidence suggest that oestrogens affect …

The transition to menopause is associated with various physiological changes, including
alterations in brain structure and function. However, menopause-related structural and …

Background and Objectives It is unknown whether there are sex-related profiles of
cardiometabolic health that contribute differently to age-related changes in brain health …

Research on age‐related memory alterations traditionally targets individuals aged≥ 65
years. However, recent studies emphasize the importance of early aging processes. We …