Objective—Liver X receptors (LXRs) are oxysterol-activated nuclear receptors regulating
reverse cholesterol transport, in part by modulating cholesterol efflux from macrophages to …

Liver X receptors (LXRs) are nuclear receptors that regulate macrophage cholesterol efflux
by inducing ATP-binding cassette transporter A1 (ABCA1) and ABCG1/ABCG4 gene …

Liver X receptors (LXR) are oxysterol-activated nuclear receptors that play a central role in
reverse cholesterol transport through up-regulation of ATP-binding cassette transporters …

Background—Liver X receptors (LXRs) are ligand-activated transcription factors involved in
the control of lipid metabolism and inflammation. Synthetic LXR agonists have been shown …

Objective—The ability of high-density lipoprotein (HDL) particles to accept cholesterol from
peripheral cells, such as lipid-laden macrophages, and to transport cholesterol to the liver …

The liver X receptors (LXRs) have been shown to affect lipoprotein plasma profile, lipid
metabolism, and reverse cholesterol transport (RCT). In the present study, we investigated …

Background The nuclear receptor liver X receptor (LXR) has two isoforms: LXRα and LXRβ.
LXR activation promotes cholesterol efflux in macrophages, but the relative importance of …

Liver X receptor (LXR) activation promotes reverse cholesterol transport (RCT) in rodents
but has major side effects (increased triglycerides and LDL-cholesterol levels) in species …

Recent studies have identified the liver X receptors (LXRα and LXRβ) as important
regulators of cholesterol metabolism and transport. LXRs control transcription of genes …

Liver X receptors (LXRs) are ligand-dependent transcription factors that are activated by
metabolites of cholesterol, oxysterols, and a number of synthetic agonists. LXRs play potent …