BACKGROUND: LBT-999 (E)-N-(4-fluorobut-2-enyl)-2β-carbomethoxy-3β-(4′-tolyl)
nortropane is a dopamine transporter (DAT) ligand.[18F] LBT-999 was first labelled with …

Copper‐mediated radiofluorination provides a quick and versatile approach for 18F‐
labeling of arenes and heteroarenes. However, this method is known to be base sensitive …

Abstract [1 8 F] Flumazenil was prepared by a new route: isotope exchange of 19 F for 18 F
under standard conditions of nucleophilic fluorination using the complex [K/K2. 2.2]+ 18 F …

β-CIT-FP [N-(3-fluoropropyl)-2β-carbomethoxy-3β-(4-iodophenyl) nortropane] is a cocaine
analogue with a high affinity for the dopamine transporter.[O-methyl-11C] β-CIT-FP ([11C] β …

We have characterized the usage of [18F] CFT (also known as [18F] WIN 35,428) as a
radioligand for in vivo studies of human dopamine transporter by PET. CFT was labeled with …

The aim of this study was to do an initial assessment of the usefulness of 2β-carbomethoxy-
3β-(4-chlorophenyl)-8-(2-18F-fluoroethyl) nortropane (18F-FECNT) PET scanning in …

Abstract Introduction Two 7-fluoroimidazobenzodiazepines (AH114726 and GEH120348),
analogs of flumazenil, were labeled with fluorine-18 and evaluated as alternative …

LBT-999 (8-((E)-4-fluoro-but-2-enyl)-3β-p-tolyl-8-aza-bicyclo [3.2. 1] octane-2β-carboxylic
acid methyl ester), a cocaine derivative belonging to a new generation of highly selective …

18F-labeled 2 β-carbomethoxy-3β-(4-chlorophenyl)-8-(− 2-fluoroethyl) nortropane ([18F]
FECNT) is a recently developed dopamine transporter ligand with potential applications in …

Introduction Present data indicate that merging beneficial structural elements from
previously published DAT-ligands highest DAT affinity, selectivity and a suitable metabolic …