Serotonin transporters (SERTs) are involved in regulating the concentration of synaptic
serotonin and present a good target for many neurologic and psychiatric disorder drugs …

This study was designed to evaluate the radiation dosimetry in human subjects for a new
radiopharmaceutical, N-(3-18F-fluoropropyl)-2β-carbomethoxy-3β-(4-iodophenyl) …

Abstract N-3-[18F] fluoropropyl-2β-carbomethoxy-3β-4-iodophenyl nortropane ([18F] FP-
CIT) is a radiopharmaceutical for dopamine transporter (DAT) imaging using positron …

The aim of this study was to develop a practical route for preparing a fluorine-18 ([18F])
labelled ligand ([18F] 1) containing [18F] fluorobenzene ring by employing the reaction of …

Positron emission tomography (PET) is a preclinical and clinical imaging technique
extensively used to study and visualize biological and physiological processes in vivo …

18 F-(E)-N-(3-iodoprop-2-enyl)-2β-carbofluoroethoxy-3β-(4′-methyl-phenyl) nortropane
(18 F-FE-PE2I) is a recently developed radioligand for in vivo quantification of the dopamine …

Parkinson disease (PD) is the second most common neurodegenerative disease. It is known
to be associated with age, hormonal imbalance, lifestyle exposures, and genetic factors, as …

30 Objectives We previously reported process comparison of microwave and thermal
methods for synthesizing the dopamine D2 receptor tracer [18 F] fallypride. In this study we …

Introduction Novel radiotracer development for imaging dopamine transporters is a subject
of interest because although [99mTc] TRODAT-1,[123I] β-CIT, and [123I] FP-CIT are …

Parkinson's disease is a progressive neurodegenerative disorder that is associated with the
loss of nerve terminals from specific brain areas, particularly in the caudate and putamen …