Background Antihistamines are used for the treatment of allergic rhinitis, allergic
conjunctivitis, chronic spontaneous urticaria and atopic eczema. Objective To study the …

Purpose H1‐antihistamines are commonly used in infants and children for the relief of
histamine‐mediated symptoms in a variety of conditions. Little is known about their safety …

Background Information about safety issues from use of asthma medications in children is
limited. Spontaneous adverse drug reaction (ADR) reports can provide information about …

Methods An observational study on all ADR notifications recorded in the French
pharmacovigilance database by the Regional Pharmacovigilance Center of Champagne …

Data on the epidemiology of adverse drug reactions (ADR), especially allergic drug
reactions, in children are rare. The reported prevalence of ADR in pediatric populations …

Background: The potential risk of adverse drug reactions (ADRs) in the paediatric population
has become a public health concern and regulatory agencies in Europe and the US have …

Background Knowledge of drug tolerance and safety in children is limited. The study of
spontaneous notifications of adverse events (AEs) can be an important source of …

Abstract Background H1‐antihistamines (AHs) are widely used for the treatment of allergic
diseases, being one of the most commonly prescribed classes of medications in pediatrics …

Adverse drug reactions (ADR) are an important medical problem. The aim of this study is to
investigate the clinical characteristics of children with ADR and to assess the tolerability of …

Aims The risk to develop adverse drug reactions (ADRs) is high for paediatric patients. This
is, amongst other reasons, due to the inevitable use of off-label and unlicensed medicines …