Background: Most examinations of the clinical efficacy of drugs used to treat depression pool
subjects across gender and age groups. This investigation compared these patient …

Background: Studies to date suggest that venlafaxine is effective, well tolerated, and safe in
a broad spectrum of patients. We examined the clinical utility and tolerability of venlafaxine …

Venlafaxine is a structurally novel compound with a biochemical and pharmacological
profile suggesting antidepressant properties. We report the results of a Phase ll, double …

Background This study was undertaken to compare the antidepressant efficacy and short-
term safety of venlafaxine with those of placebo in hospitalized patients with major …

This was a randomized, double-blind, placebo-controlled comparison of the efficacy and
safety of once-daily venlafaxine extended release (XR) and venlafaxine immediate release …

Purpose This study aimed to investigate the influence of diagnosis, body weight, sex, age,
smoking, formulations, and concomitant drugs on steady‐state dose‐corrected serum …

Purpose To explore the potential factors impacting the efficacy of venlafaxine extended
release (ER) and treatment differences between 75 mg/day and 75–225 mg/day dose in …

Purpose/Background This post hoc analysis examined the time point at which clinically
significant improvement in major depressive disorder (MDD) symptoms occurs with …

Objective: To evaluate data supporting the ability of venlafaxine, an antidepressant with a
dual mechanism of action, to produce remission from depression. Method: Review of …

We assessed the effect of body weight and BMI on plasma concentrations of venlafaxine
(VEN), O-desmethylvenlafaxine (ODVEN), active moiety (AM= VEN+ ODVEN), and dose …