Aim: Genipin is reported to stimulate the insertion of multidrug resistance protein 2 (Mrp2) in
the bile canalicular membrane, thereby causing choleresis by the increased the biliary …

Aim: Genipin, a metabolite of geniposide, is reported to stimulate the insertion of multidrug
resistance protein 2 (Mrp2) in the bile canalicular membrane, and to cause choleresis by …

Aim Penicillin G is reported to increase bile flow by increasing biliary glutathione excretion,
as well as the biliary excretion of penicillin G itself. In order to study the effect of penicillin G …

Abstract Inchin‐ko‐to (ICKT), an herbal medicine, and its ingredients exert potent choleretic
effects by a “bile acid‐independent” mechanism. The current study was designed to …

Abstract Estradiol‐17β‐glucuronide (E217G) is a cholestatic agent and is considered to be
related to the pathogenesis of intrahepatic cholestasis of pregnancy. In the current study, we …

Estradiol-17β-glucuronide is a cholestatic agent and is considered to be related to the
pathogenesis of intrahepatic cholestasis of pregnancy. We previously reported that biliary …

The intravenous administration of dimethylethanolamine in the rat promotes a selective
enrichment of liver membranes with polyunsaturated phosphatidylcholines. The effect of …

The effect of the co-infusion of ursodeoxycholate and its taurine conjugate, 3-O-glucuronide
and 3, 7-disulfate on estradiol-17β-glucuronide-induced cholestasis was examined …

The effect of spironolactone (SL) administration on 17α-ethynylestradiol (EE)-induced
cholestasis was studied, with emphasis on expression and activity of Mrps. Adult male …

The present study evaluates the roles of the multidrug resistance-1 P-glycoprotein,
Mdr1a/1b, the bile salt export pump (Bsep), and the multidrug resistance-associated protein …