Demethylenetetrahydroberberine protects dopaminergic neurons in a mouse model of Parkinson's disease

WEN Jing, YQ Zhang, LIU Dong-Qing… - Chinese Journal of …, 2022 - Elsevier
Parkinson's disease (PD) is a multifactorial disorder of the nervous system where a
progressive loss of dopaminergic neurons exist. However, the pathogenesis of PD remains …

Berberine prevents nigrostriatal dopaminergic neuronal loss and suppresses hippocampal apoptosis in mice with Parkinson's disease

M Kim, KIHO Cho, MS Shin… - International …, 2014 - spandidos-publications.com
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the
selective loss of nigral dopaminergic neurons and a reduction in striatal dopaminergic fibers …

Treatment of Parkinson's disease in Zebrafish model with a berberine derivative capable of crossing blood brain barrier, targeting mitochondria, and convenient for …

L Wang, W Sheng, Z Tan, Q Ren, R Wang… - … and Physiology Part C …, 2021 - Elsevier
Berberine is a famous alkaloid extracted from Berberis plants and has been widely used as
medications and functional food additives. Recent studies reveal that berberine exhibits …

Bruceine D elevates Nrf2 activation to restrain Parkinson's disease in mice through suppressing oxidative stress and inflammatory response

Y Yang, F Kong, Q Ding, Y Cai, Y Hao… - … and Biophysical Research …, 2020 - Elsevier
Parkinson's disease (PD) is neurodegenerative disease, featured by a loss of dopaminergic
neurons in the substantia nigra pars compacta (SNpc), characteristic motor symptoms and …

[PDF][PDF] To determine the Effect of Berberine on 6-OHDA induced memory impairment in Parkinson's disease in rodents

V Kahale, A Mhaiskar, P Shelat, RU Pooja… - The Pharma …, 2014 - researchgate.net
The relevant doses of Berberine administration in present preclinical study states that
neurotoxicity induced by 6-Hydroxydopamine is remarkably neuroprotective in male wistar …

DMTHB ameliorates memory impairment in Alzheimer's disease mice through regulation of neuroinflammation

Y Zhang, D Liu, X Yao, J Wen, Y Wang, Y Zhang - Neuroscience Letters, 2022 - Elsevier
Background Alzheimer's disease (AD) is one of the most prevalent neurodegenerative
diseases. Growing evidence suggested that AD is associated with neuroinflammation …

Neurotrophic and neuroprotective effects of tripchlorolide, an extract of Chinese herb Tripterygium wilfordii Hook F, on dopaminergic neurons

FQ Li, XX Cheng, XB Liang, XH Wang, B Xue… - Experimental …, 2003 - Elsevier
It has been reported recently that the immunosuppressant FK506 produced neurotrophic
and neuroprotective effects on dopaminergic neurons in vitro and in vivo. We investigated …

[HTML][HTML] Can berberine serve as a new therapy for parkinson's disease?

E Dadgostar, M Moghanlou, M Parvaresh… - Neurotoxicity …, 2022 - Springer
Parkinson's disease (PD) is a neurodegenerative disorder characterized by dopaminergic
neurodegeneration and deposition of alpha-synuclein. Mechanisms associated with PD …

Neuroprotective effect of Dabuyin pill, Qianzheng powder and combined formula on Parkinson's disease mice brain.

HX He Xin, SHM Sun HongMei, WHX Wu HaiXia… - 2010 - cabidigitallibrary.org
Objective: To investigate the neuroprotective effect of Dabuyin pill, Qianzheng powder and
combined formula on dopaminergic (DAnergic) neurons of 1-methy-4-phenyl-1, 2, 3, 6 …

Berberine protects 6-hydroxydopamine-induced human dopaminergic neuronal cell death through the induction of heme oxygenase-1

J Bae, D Lee, YK Kim, M Gil, JY Lee, KJ Lee - Molecules and cells, 2013 - Springer
Berberine (BBR) is one of the major alkaloids and has been reported to have a variety of
pharmacologic effects, including inhibition of cell cycle progression. Here, we investigated …