HIV-1 heterogeneity and cytokines: neuropathogenesis
P Shapshak, I Nagano, K Xin, W Bradley… - The brain immune axis …, 1995 - Springer
Mild manifestations (HIV-1 associated minor cognitive/motor disorder), severe
manifestations (HIV-1 associated dementia complex and HIV-1 associated myelopathy), and …
manifestations (HIV-1 associated dementia complex and HIV-1 associated myelopathy), and …
HIV-1 clade-specific differences in the induction of neuropathogenesis
Human immunodeficiency virus (HIV)-associated dementia (HAD) is common among clade
B HIV-infected individuals, but less common and less severe among individuals infected …
B HIV-infected individuals, but less common and less severe among individuals infected …
HIV‐1, macrophages, glial cells, and cytokines in AIDS nervous system disease
JE Merrill, ISY Chen - The FASEB journal, 1991 - Wiley Online Library
Hallmarks of central nervous system (GNS) disease in AIDS patients are headaches, fever,
subtle cognitive changes, abnormal reflexes, and ataxia. Dementia and severe sensory and …
subtle cognitive changes, abnormal reflexes, and ataxia. Dementia and severe sensory and …
Cytokine dysregulation in HIV-associated neurological disease
AIDS is associated with three major neurological syndromes: dementia (HIVD), vacuolar
myelopathy (VM) and plainful sensory neuropathy (PSN). The pathogenesis of these …
myelopathy (VM) and plainful sensory neuropathy (PSN). The pathogenesis of these …
Role of immune activation and cytokine expression in HIV-1-associated neurologic diseases
M Yoshioka, WG Bradley, P Shapshak, I Nagano… - Advances in …, 1995 - Elsevier
Central nervous system (CNS) involvement is common during human immunodeficiency
virus type-1 (HIV-1) infection. The neurologic disease of the CNS most frequently observed …
virus type-1 (HIV-1) infection. The neurologic disease of the CNS most frequently observed …
The neuropathogenesis of HIV‐1 infection
JL Buescher, S Gross, HE Gendelman… - Handbook of clinical …, 2007 - Elsevier
Publisher Summary Significant neurological complications associated with HIV-1 infection
occur years after an acute viral seroconversion reaction and are commonly coincident with …
occur years after an acute viral seroconversion reaction and are commonly coincident with …
Independent evolution of HIV type 1 in different brain regions
P Shapshak, DM Segal, KA Crandall… - AIDS research and …, 1999 - liebertpub.com
HIV-1-associated brain pathology exhibits regional variability and we therefore studied the
genetic differences in the V1-V5 domains of the HIV env gene in up to four regions of brain …
genetic differences in the V1-V5 domains of the HIV env gene in up to four regions of brain …
Human immunodeficiency virus type 1 compartmentalization in the central nervous system
CK Petito - Journal of neurovirology, 2004 - Taylor & Francis
HIV-1 replicates in monocyte-derived cells in multiple organ systems; in the central nervous
system, productive infection is confined to monocyte lineage cells in the brain. In addition …
system, productive infection is confined to monocyte lineage cells in the brain. In addition …
Cellular reservoirs of HIV-1 in the central nervous system of infected individuals: identification by the combination of: in situ: polymerase chain reaction and …
O Bagasra, E Lavi, L Bobroski, K Khalili, JP Pestaner… - Aids, 1996 - journals.lww.com
Objectives: The majority of HIV-1-infected individuals manifest a plethora of central nervous
system (CNS) diseases unrelated to opportunistic infections, including AIDS dementia …
system (CNS) diseases unrelated to opportunistic infections, including AIDS dementia …
Unifying hypothesis for the pathogenesis of HIV-associated dementia complex, vacuolar myelopathy, and sensory neuropathy
WR Tyor, SL Wesselingh, JW Griffin… - JAIDS Journal of …, 1995 - journals.lww.com
Neurological diseases associated with HIV infection include dementia, vacuolar myelopathy,
and sensory neuropathy. Although in vitro studies suggest that other nervous system cell …
and sensory neuropathy. Although in vitro studies suggest that other nervous system cell …