Background Lung adenocarcinoma (LUAD) patients have a dismal survival rate because of
cancer metastasis and drug resistance. The study aims to identify the genes that …

Background Non-small cell lung cancer (NSCLC) shows the highest morbidity among
malignant tumors worldwide. Despite improvements of diagnosis and treatment, patient …

Aim: To explore the roles of GMDS-AS1 in the epithelial–mesenchymal transition (EMT) of
lung adenocarcinoma (LUAD). Materials & methods: Cell functions were detected by flow …

Lung cancer is one of the leading causes of cancer-associated death, with the etiology
largely unknown. The aim of this study was to identify key driver genes with therapeutic …

DUSP22, an atypical dual-specificity phosphatase enzyme, plays a significant role in
regulating multiple kinase signaling pathways by dephosphorylation. Our study …

Purpose This study aims to investigate the potential role of DUS4L (dihydrouridine synthase
4 like) in lung adenocarcinoma (LUAD) and explore its associated pathways in human …

Non-small-cell lung cancer (NSCLC) is the second most common cancer worldwide, and
most deaths are associated with epithelial–mesenchymal transition (EMT). Therefore, this …

Purpose: Lung cancer is the leading cause of cancer-related death in the world, and
emerging evidences suggest that lung cancer stem cells (CSC) are associated with its poor …

For lung adenocarcinoma (LUAD), patients of different stages have strong heterogeneity,
and their overall prognosis varies greatly. Thus, exploration of novel biomarkers to better …

Abstract Dual-specificity phosphatase 8 (DUSP8) plays an important role as a selective c-
Jun N-terminal kinase (JNK) phosphatase in mitogen-activated protein kinase (MAPK) …