Pediatric acute myeloid leukemia: updates on biology, risk stratification, and therapy

CW Elgarten, R Aplenc - Current Opinion in Pediatrics, 2020 - journals.lww.com
Further incorporation of genomic and molecular data in pediatric AML will allow for
additional refinements in risk stratification to enable the tailoring of treatment intensity. These …

Acute myeloid leukemia in children: Current status and future directions

T Taga, D Tomizawa, H Takahashi… - Pediatrics …, 2016 - Wiley Online Library
Acute myeloid leukemia (AML) accounts for 25% of pediatric leukemia and affects
approximately 180 patients annually in Japan. The treatment outcome for pediatric AML has …

Acute myeloid leukemia in children: emerging paradigms in genetics and new approaches to therapy

SE Conneely, AM Stevens - Current oncology reports, 2021 - Springer
Abstract Purpose of Review Acute myeloid leukemia (AML) in children remains a
challenging disease to cure with suboptimal outcomes particularly when compared to the …

Current management of childhood acute myeloid leukemia

JE Rubnitz - Pediatric Drugs, 2017 - Springer
The outcome for children with acute myeloid leukemia (AML) has improved significantly over
the past 30 years, with complete remission and overall survival rates exceeding 90 and …

[HTML][HTML] Pediatric acute myeloid leukemia: towards high-quality cure of all patients

GJL Kaspers, CM Zwaan - haematologica, 2007 - haematologica.org
Prognosis of childhood acute myeloid leukemia (AML) has improved significantly over the
past decades, from nearly no child surviving to a present probability of cure of approximately …

How I treat pediatric acute myeloid leukemia

JE Rubnitz - Blood, The Journal of the American Society of …, 2012 - ashpublications.org
Acute myeloid leukemia is a heterogeneous disease that accounts for approximately 20% of
acute leukemias in children and adolescents. Despite the lack of targeted therapy for most …

Acute myeloid leukemia

JE Rubnitz, B Gibson, FO Smith - Pediatric clinics of North America, 2008 - Elsevier
Acute myeloid leukemia (AML) is a heterogeneous group of leukemias that result from clonal
transformation of hematopoietic precursors through the acquisition of chromosomal …

Pediatric AML: from biology to clinical management

JDE De Rooij, CM Zwaan… - Journal of clinical …, 2015 - mdpi.com
Pediatric acute myeloid leukemia (AML) represents 15%–20% of all pediatric acute
leukemias. Survival rates have increased over the past few decades to~ 70%, due to …

Childhood acute myeloid leukaemia

JE Rubnitz, H Inaba - British journal of haematology, 2012 - Wiley Online Library
Although acute myeloid leukaemia (AML) has long been recognized for its morphological
and cytogenetic heterogeneity, recent high‐resolution genomic profiling has demonstrated a …

Biology, risk stratification, and therapy of pediatric acute leukemias: an update

CH Pui, WL Carroll, S Meshinchi… - Journal of clinical …, 2011 - ascopubs.org
Purpose We review recent advances in the biologic understanding and treatment of
childhood acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML), identify …