[HTML][HTML] Asc-Seurat: analytical single-cell Seurat-based web application

WJ Pereira, FM Almeida, D Conde, KM Balmant… - BMC …, 2021 - Springer
Background Single-cell RNA sequencing (scRNA-seq) has revolutionized the study of
transcriptomes, arising as a powerful tool for discovering and characterizing cell types and …

[HTML][HTML] Single-cell RNA sequencing and its combination with protein and DNA analyses

JR Choi, KW Yong, JY Choi, AC Cowie - Cells, 2020 - mdpi.com
Heterogeneity in cell populations poses a significant challenge for understanding complex
cell biological processes. The analysis of cells at the single-cell level, especially single-cell …

[HTML][HTML] Comparative analysis of single-cell RNA sequencing methods

C Ziegenhain, B Vieth, S Parekh, B Reinius… - Molecular cell, 2017 - cell.com
Single-cell RNA sequencing (scRNA-seq) offers new possibilities to address biological and
medical questions. However, systematic comparisons of the performance of diverse scRNA …

Scater: pre-processing, quality control, normalization and visualization of single-cell RNA-seq data in R

DJ McCarthy, KR Campbell, ATL Lun, QF Wills - Bioinformatics, 2017 - academic.oup.com
Motivation Single-cell RNA sequencing (scRNA-seq) is increasingly used to study gene
expression at the level of individual cells. However, preparing raw sequence data for further …

Computational methods for single-cell RNA sequencing

B Hie, J Peters, SK Nyquist, AK Shalek… - Annual Review of …, 2020 - annualreviews.org
Single-cell RNA sequencing (scRNA-seq) has provided a high-dimensional catalog of
millions of cells across species and diseases. These data have spurred the development of …

Single‐cell RNA sequencing technologies and applications: A brief overview

D Jovic, X Liang, H Zeng, L Lin, F Xu… - Clinical and …, 2022 - Wiley Online Library
Single‐cell RNA sequencing (scRNA‐seq) technology has become the state‐of‐the‐art
approach for unravelling the heterogeneity and complexity of RNA transcripts within …

[HTML][HTML] A review of single-cell RNA-Seq annotation, integration, and cell–cell communication

C Cheng, W Chen, H Jin, X Chen - Cells, 2023 - mdpi.com
Single-cell RNA sequencing (scRNA-seq) has emerged as a powerful tool for investigating
cellular biology at an unprecedented resolution, enabling the characterization of cellular …

[HTML][HTML] Reproducibility of methods to detect differentially expressed genes from single-cell RNA sequencing

T Mou, W Deng, F Gu, Y Pawitan, TN Vu - Frontiers in genetics, 2020 - frontiersin.org
Detection of differentially expressed genes is a common task in single-cell RNA-seq (scRNA-
seq) studies. Various methods based on both bulk-cell and single-cell approaches are in …

A statistical simulator scDesign for rational scRNA-seq experimental design

WV Li, JJ Li - Bioinformatics, 2019 - academic.oup.com
Motivation Single-cell RNA sequencing (scRNA-seq) has revolutionized biological sciences
by revealing genome-wide gene expression levels within individual cells. However, a critical …

Application of deep learning on single-cell RNA sequencing data analysis: a review

M Brendel, C Su, Z Bai, H Zhang… - Genomics …, 2022 - academic.oup.com
Single-cell RNA sequencing (scRNA-seq) has become a routinely used technique to
quantify the gene expression profile of thousands of single cells simultaneously. Analysis of …