Scater: pre-processing, quality control, normalization and visualization of single-cell RNA-seq data in R
Motivation Single-cell RNA sequencing (scRNA-seq) is increasingly used to study gene
expression at the level of individual cells. However, preparing raw sequence data for further …
expression at the level of individual cells. However, preparing raw sequence data for further …
Computational methods for single-cell RNA sequencing
Single-cell RNA sequencing (scRNA-seq) has provided a high-dimensional catalog of
millions of cells across species and diseases. These data have spurred the development of …
millions of cells across species and diseases. These data have spurred the development of …
A statistical simulator scDesign for rational scRNA-seq experimental design
Motivation Single-cell RNA sequencing (scRNA-seq) has revolutionized biological sciences
by revealing genome-wide gene expression levels within individual cells. However, a critical …
by revealing genome-wide gene expression levels within individual cells. However, a critical …
Single‐cell RNA sequencing technologies and applications: A brief overview
D Jovic, X Liang, H Zeng, L Lin, F Xu… - Clinical and …, 2022 - Wiley Online Library
Single‐cell RNA sequencing (scRNA‐seq) technology has become the state‐of‐the‐art
approach for unravelling the heterogeneity and complexity of RNA transcripts within …
approach for unravelling the heterogeneity and complexity of RNA transcripts within …
[HTML][HTML] Reproducibility of methods to detect differentially expressed genes from single-cell RNA sequencing
Detection of differentially expressed genes is a common task in single-cell RNA-seq (scRNA-
seq) studies. Various methods based on both bulk-cell and single-cell approaches are in …
seq) studies. Various methods based on both bulk-cell and single-cell approaches are in …
Application of deep learning on single-cell RNA sequencing data analysis: a review
Single-cell RNA sequencing (scRNA-seq) has become a routinely used technique to
quantify the gene expression profile of thousands of single cells simultaneously. Analysis of …
quantify the gene expression profile of thousands of single cells simultaneously. Analysis of …
[HTML][HTML] A hitchhiker's guide to single-cell transcriptomics and data analysis pipelines
Single-cell transcriptomics (SCT) is a tour de force in the era of big omics data that has led to
the accumulation of massive cellular transcription data at an astounding resolution of single …
the accumulation of massive cellular transcription data at an astounding resolution of single …
[HTML][HTML] A step-by-step workflow for low-level analysis of single-cell RNA-seq data with Bioconductor
Single-cell RNA sequencing (scRNA-seq) is widely used to profile the transcriptome of
individual cells. This provides biological resolution that cannot be matched by bulk RNA …
individual cells. This provides biological resolution that cannot be matched by bulk RNA …
bigSCale: an analytical framework for big-scale single-cell data
Single-cell RNA sequencing (scRNA-seq) has significantly deepened our insights into
complex tissues, with the latest techniques capable of processing tens of thousands of cells …
complex tissues, with the latest techniques capable of processing tens of thousands of cells …
Full-length single-cell RNA sequencing with smart-seq2
S Picelli - Single Cell Methods: Sequencing and Proteomics, 2019 - Springer
In the last few years single-cell RNA sequencing (scRNA-seq) has enabled the investigation
of cellular heterogeneity at the transcriptional level, the characterization of rare cell types as …
of cellular heterogeneity at the transcriptional level, the characterization of rare cell types as …