The NLRP3 inflammasome is a cytoplasmic multiprotein complex, the assembly of which
can be initiated in response to various exogenous or endogenous danger signals …

Inflammasomes are multi-protein signaling complexes that trigger the activation of
inflammatory caspases and the maturation of interleukin-1β. Among various inflammasome …

Inflammasomes are cytosolic multiprotein complexes that cause the release of biologically
active interleukin‐1β. The best‐characterized inflammasome is the NLRP3 (nucleotide …

In response to diverse pathogenic and danger signals, the cytosolic activation of the NLRP3
(NOD-, LRR-, and pyrin domain-containing (3)) inflammasome complex is a critical event in …

Abstract The NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome is
a multiprotein complex involved in the release of mature interleukin-1β and triggering of …

Inflammasomes play a crucial role in innate immunity by serving as signaling platforms
which deal with a plethora of pathogenic products and cellular products associated with …

The NLRP3 inflammasome is activated in response to a variety of signals that are indicative
of damage to the host including tissue damage, metabolic stress, and infection. Upon …

Introduction: Inflammatory reactions, including those mediated by the NLRP3
inflammasome, maintain the body's homeostasis by removing pathogens, repairing …

The NOD-like receptor protein 3 (NLRP3) inflammasome is a protein complex that regulates
innate immune responses by activating caspase-1 and the inflammatory cytokines …

The NLRP3 inflammasome regulates innate immune and inflammatory responses by
promoting pro-inflammatory cytokines such as IL-18 and IL-1β. NLRP3 is one of the main …