[HTML][HTML] Clinical utility of the Prostate Health Index (phi) for biopsy decision management in a large group urology practice setting

J White, BV Shenoy, RF Tutrone, LI Karsh… - Prostate cancer and …, 2018 - nature.com
Background Deciding when to biopsy a man with non-suspicious DRE findings and tPSA in
the 4–10 ng/ml range can be challenging, because two-thirds of such biopsies are typically …

Use of the Prostate Health Index for detection of prostate cancer: results from a large academic practice

JJ Tosoian, SC Druskin, D Andreas… - Prostate cancer and …, 2017 - nature.com
Background: The Prostate Health Index (phi) outperforms PSA and other PSA derivatives for
the diagnosis of prostate cancer (PCa). The impact of phi testing in the real-world clinical …

Multicenter evaluation of the prostate health index to detect aggressive prostate cancer in biopsy naive men

C De La Calle, D Patil, JT Wei, DS Scherr… - The Journal of …, 2015 - auajournals.org
Purpose: We evaluated the ability of PHI to discriminate aggressive prostate cancer from
indolent or no cancer in a biopsy naïve population. Materials and Methods: Two …

Prostate health index significantly reduced unnecessary prostate biopsies in patients with PSA 2‐10 ng/mL and PSA> 10 ng/mL: Results from a Multicenter Study in …

R Na, D Ye, J Qi, F Liu, BT Helfand, CB Brendler… - The …, 2017 - Wiley Online Library
Background The performance of prostate health index (phi) in predicting prostate biopsy
outcomes has been well established for patients with prostate‐specific antigen (PSA) values …

[HTML][HTML] The prostate health index: its utility in prostate cancer detection

A Lepor, WJ Catalona, S Loeb - The Urologic Clinics of North …, 2016 - ncbi.nlm.nih.gov
The prostate health index (phi) is a FDA-approved blood test combining total, free and−
2proPSA with greater specificity than free and total PSA for clinically-significant prostate …

The prostate health index selectively identifies clinically significant prostate cancer

S Loeb, MG Sanda, DL Broyles, SS Shin… - The Journal of …, 2015 - auajournals.org
Purpose: The Prostate Health Index (phi) is a new test combining total, free and [-2] proPSA
into a single score. It was recently approved by the FDA and is now commercially available …

Clinical performance of prostate health index in men with tPSA> 10 ng/ml: Results from a multicentric European study

M Lazzeri, G Lughezzani, A Haese… - … Oncology: Seminars and …, 2016 - Elsevier
Background Evidence regarding the diagnostic accuracy of a [-2] proPSA derivative, namely,
the prostate health index (PHI), to predict the presence of prostate cancer (PCa) in …

Prostate Health Index density improves detection of clinically significant prostate cancer

JJ Tosoian, SC Druskin, D Andreas, P Mullane… - BJU …, 2017 - Wiley Online Library
Objectives To explore the utility of Prostate Health Index (PHI) density for the detection of
clinically significant prostate cancer (PC a) in a contemporary cohort of men presenting for …

Multicenter European external validation of a Prostate Health Index–based nomogram for predicting prostate cancer at extended biopsy

G Lughezzani, M Lazzeri, A Haese, T McNicholas… - European urology, 2014 - Elsevier
Background External validation of a prediction tool is mandatory to assess the tool's
accuracy and generalizability within different patient cohorts. Objective To externally validate …

Accuracy of the prostate health index versus the urinary prostate cancer antigen 3 score to predict overall and significant prostate cancer at initial biopsy

T Seisen, M Rouprêt, D Brault, P Léon… - The …, 2015 - Wiley Online Library
BACKGROUND It remains unclear whether the Prostate Health Index (PHI) or the urinary
Prostate‐Cancer Antigen 3 (PCA‐3) score is more accurate at screening for prostate cancer …