Heterogeneous functions of macrophages in human immune systems have renewed interest
in targeting of drugs to these cells. Various carrier systems have emerged to deliver drugs to …

As the role of monocytes and macrophages in a range of diseases is better understood,
strategies to target these cell types are of growing importance both scientifically and …

Particulate systems in the form of liposomes, polymeric micelles, polymeric nano-and
microparticles, and many others offer a rational approach for selective delivery of therapeutic …

Macrophages have been extensively used in the development of drug delivery systems, as
they can prolong the circulation and release of drugs, extend their half-life, increase their …

Introduction: Targeted drug delivery to the macrophages appears to be an attractive
proposition to improve therapeutic efficacy of enclosed drug. Thus, macrophages can be …

Macrophages are prevalent in the body and have roles in almost every aspect of human
biology. They have often been considered a subject to avoid during drug delivery. However …

Liposomes have gained extensive attention as carriers for a wide range of drugs due to
being both nontoxic and biodegradable as they are composed of substances naturally …

Many investigators have proposed that liposomes be utilized as carriers to deliver drugs.
One perceived difficulty in this approach has been that liposomes are cleared rapidly by …

Although hydrophilic small molecule drugs are widely used in the clinic, their rapid
clearance, suboptimal biodistribution, low intracellular absorption and toxicity can limit their …

Currently used pharmaceutical nanocarriers, such as liposomes, micelles, nanoemulsions,
polymeric nanoparticles and many others demonstrate a broad variety of useful properties …